Overview

  • Product nameAnti-GRID2 antibodySee all GRID2 primary antibodies ...
  • Description
    Mouse monoclonal to GRID2
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: DTLPTRQALE QISDFRNTHI TTTTFIPEQI QTLSRTLSAK AASGFTFGNV PEHRTGPFRH RAPNGGFFRS PIKTMSSIPY QPTPTLGLNL GNDPDRGTSI , corresponding to amino acids 908-1008 of Human GRID2

Properties

Applications

Our Abpromise guarantee covers the use of ab55165 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceGlutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. Mouse GRID2 is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death.
    • Cellular localizationCell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane;
    • Database links
    • Alternative names
      • GLUR D2 antibody
      • GluR delta 2 antibody
      • GLURD 2 antibody
      • GLURD2 antibody
      • Glutamate receptor delta 2 subunit antibody
      • Glutamate receptor ionotropic delta 2 antibody
      • GRID 2 antibody
      • MGC117022 antibody
      • MGC117023 antibody
      • MGC117024 antibody
      see all

    Anti-GRID2 antibody images

    • Western blot against tagged recombinant protein immunogen using ab55165 GRID2 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-GRID2 antibody (ab55165)

    ab55165 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"