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Overview

  • Product nameGRO beta protein (Mouse)See all GRO beta proteins and peptides ...
  • Protein descriptionRecombinant full length mouse GRO beta; 73 amino acids, 7849 Dalton. Swiss ID = P10889
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab73813 is purified by proprietary chromatographic techniques. Purity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
  • FormLyophilised:Reconstitute in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
  • Storage instructionsAliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
  • Concentration information loading...
  • Sequence notesThe sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Val-Ala-Ser.
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab73813 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies
    SDS-PAGE
  • Application notesFuncS: Use at an assay dependent dilution.
    The Biological activity was determined by measuring the dose dependent mobilization of intracellular calcium (calcium flux) with human neutrophils. Significant calcium mobilization is observed with >5 ng/ml of recombinant mouse GRO beta.

    SDS-PAGE: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        C-X-C motif chemokine 2Chemokine (C X C motif) ligand 2Chemokine, CXC motif, ligand 2
        CINC 2aCINC2aCINC3CXC chemokineCXCL 2CXCL2CXCL2_HUMANCytokine-induced neutrophil chemoattractant 3GRO 2GRO bGRO protein, betaGro-betaGRO-beta(5-73)GRO-beta-TGRO2GRO2 oncogeneGRObGRObetaGrowth regulated protein betaGrowth-regulated protein betaGROXHematopoietic synergistic factorHSFMacrophage inflammatory protein 2Macrophage inflammatory protein 2 alphaMacrophage inflammatory protein 2-alphaMelanoma growth stimulatory activity betaMGSA bMGSA betaMGSAbetaMIP 2MIP 2aMIP2MIP2 alphaMIP2-alphaMIP2AMIP2alphaSB-251353ScybSCYB 2SCYB2Small inducible cytokine subfamily B, member 2
      see all
  • FunctionProduced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
  • Sequence similaritiesBelongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications    The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P19875 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for GRO beta protein (Mouse) (ab73813)

    ab73813 has not yet been referenced specifically in any publications.

    Publishing research using ab73813 ? Please let us know so that we can cite the reference in this datasheet

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