(1742-1)
Anti-GSK3 alpha antibody [EP793Y] (ab40870)
Overview
- Product nameAnti-GSK3 alpha antibody [EP793Y]See all GSK3 alpha primary antibodies ...
- DescriptionRabbit monoclonal [EP793Y] to GSK3 alpha
- Tested applicationsWB, IHC-P, ICC, IP more details
- Species reactivityReacts with: Mouse, Rat, Human
- Immunogen
Synthetic peptide corresponding to residues near the N-terminal residues of Human GSK3 alpha.
- Positive controlHeLa cell lysate; human breast carcinoma tissue.
- General notesProduced under U.S. Patent No. 5,675,063.
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
- PurityTissue culture supernatant
- Clonality Monoclonal
- Clone numberEP793Y
- IsotypeIgG
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab40870 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | WB: 1/5000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa). |
| IHC-P | IHC-P: Use at an assay dependent dilution. |
| ICC | ICC: 1/50 - 1/100. |
| IP | IP: 1/50. |
Target
- FunctionImplicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.
- Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Contains 1 protein kinase domain. -
Database links
- Entrez Gene: 2931 Human
- Entrez Gene: 2931 Human
- Entrez Gene: 606496 Mouse
- Entrez Gene: 50686 Rat
- Omim: 606784 Human
- SwissProt: P49840 Human
- SwissProt: P49840 Human
- SwissProt: Q2NL51 Mouse
- SwissProt: P18265 Rat
- Unigene: 466828 Human
- Unigene: 294664 Mouse
- Unigene: 36807 Rat
see all
Target information above from: UniProt accession
P49840
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- DKFZp686D0638 antibodyGlycogen synthase kinase 3 alpha antibodyGlycogen synthase kinase-3 alpha antibody
- GSK 3 alpha antibodyGSK 3 alpha antibodyGSK 3A antibodyGSK-3 alpha antibodyGSK3A antibodyGSK3A_HUMAN antibodyGSK3alpha antibodySerine/threonine protein kinase GSK3A antibody
see all
Anti-GSK3 alpha antibody [EP793Y] images
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![Western blot - GSK3 alpha antibody [EP793Y] (ab40870)](http://a.abcam.com/ps/datasheet/Images/40/ab40870/ab40870wb.jpg)
Western blot - GSK3 alpha antibody [EP793Y] (ab40870)Anti-GSK3 alpha antibody [EP793Y] (ab40870) at 1/5000 dilution + 10ug HeLa cell lysate.
Predicted band size : 51 kDa
Observed band size : 51 kDa -
![Immunohistochemistry (Paraffin-embedded sections) - GSK3 alpha antibody [EP793Y] (ab40870)](http://a.abcam.com/ps/datasheet/Images/40/ab40870/ab40870IHCP.jpg)
Immunohistochemistry (Paraffin-embedded sections) - GSK3 alpha antibody [EP793Y] (ab40870)ab4870 at 1/50 dilution, staining GSK3 alpha in Human breast carcinoma tissue by Immunohistochemistry, Paraffin embedded section.
References for Anti-GSK3 alpha antibody [EP793Y] (ab40870)
This product has been referenced in:
- Yamaguchi N et al. Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol 300:H2187-95 (2011). WB ; Mouse . Read more (PubMed: 21421818) »
- Yamauchi K & Kurosaka A Expression and function of glycogen synthase kinase-3 in human hair follicles. Arch Dermatol Res 302:263-70 (2010). Read more (PubMed: 19705135) »
