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Anti-GSK3 alpha antibody [EP793Y] (ab40870)

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Overview

Product name

Anti-GSK3 alpha antibody [EP793Y]
See all GSK3 alpha products (13) ...

Description

Rabbit monoclonal [EP793Y] to GSK3 alpha

Tested applications

WB, IHC-P, ICC, IPmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic peptide corresponding to residues near the N-terminal residues of Human GSK3 alpha.

Positive control

HeLa cell lysate; human breast carcinoma tissue.

General notes

Produced under U.S. Patent No. 5,675,063.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

EP793Y

Isotype

IgG

Research areas

Cardiovascular >> Heart >> Hypertrophy >> Other
Cardiovascular >> Heart >> Apoptosis
Cardiovascular >> Atherosclerosis >> Diabetes associated
Stem Cells >> Signaling Pathways >> Wnt >> Cytoplasmic
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> Other Kinases
Cell Biology >> Cell Cycle >> Kinases/Phosphatases >> Cdks

  • Western blot - GSK3 alpha antibody [EP793Y] (ab40870)Western blot - GSK3 alpha antibody [EP793Y] (ab40870) image (enlarge)

  • Immunohistochemistry (Paraffin-embedded sections) - GSK3 alpha antibody [EP793Y] (ab40870)Immunohistochemistry (Paraffin-embedded sections) - GSK3 alpha antibody [EP793Y] (ab40870) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab40870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/5000. Detects a ba...Read more →

    WB: 1/5000. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

  • 1 Image

    IHC-P

     IHC-P: 1/50 - 1/100.

    IHC-P: 1/50 - 1/100.

  • ICC

     ICC: 1/50 - 1/100.

    ICC: 1/50 - 1/100.

  • IP

     IP: 1/50.

    IP: 1/50.

Target

Function

Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Contains 1 protein kinase domain.

Target information above from: UniProt accessionP49840 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • GSK 3 alpha antibody
  • DKFZp686D0638 antibody
  • Glycogen synthase kinase 3 alpha antibody
  • Glycogen synthase kinase-3 alpha antibody
  • GSK 3 alpha antibody
  • GSK 3A antibody
  • GSK-3 alpha antibody
  • GSK3A antibody
  • GSK3A_HUMAN antibody
  • GSK3alpha antibody
  • Serine/threonine protein kinase GSK3A antibody
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Database links

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Anti-GSK3 alpha antibody [EP793Y] images:

  Western blot - GSK3 alpha antibody [EP793Y] (ab40870)

Western blot - GSK3 alpha antibody [EP793Y] (ab40870)

Anti-GSK3 alpha antibody [EP793Y] (ab40870) at 1/5000 dilution + 10ug HeLa cell lysate.

Predicted band size : 51 kDa
Observed band size : 51 kDa

  Immunohistochemistry (Paraffin-embedded sections) - GSK3 alpha antibody [EP793Y] (ab40870)

Immunohistochemistry (Paraffin-embedded sections) - GSK3 alpha antibody [EP793Y] (ab40870)

ab4870 at 1/50 dilution, staining GSK3 alpha in Human breast carcinoma tissue by Immunohistochemistry, Paraffin embedded section.

References for Anti-GSK3 alpha antibody [EP793Y] (ab40870)

This product has been referenced in:

  • Yamaguchi N  et al. Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol 300:H2187-95 (2011). WB; Mouse.Read more (PubMed: 21421818) »

See 1 publication for this product

Publishing research using ab40870? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"