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Products:Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Overview
Product name
GSTM1 + GSTM2 peptide (207-217)
Protein description
Synthetic peptide: C-VFSKMAVWGNK, corresponding to C terminal amino acids 207-217 of Human GSTM1 + GSTM2 This peptide was used as an immunogen for ab27489 - GSTM1 + GSTM2 antibody.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Concentration
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Sequence
C-VFSKMAVW GNK
Research areas
Signal Transduction >> Metabolism >> Drug metabolism
Tags & Cell Markers >> Cell Type Markers >> Tumor Associated
Protein info
Relevance
Glutathione S transferases are encoded by two distinct supergene families and a total of eight distinct classes of the soluble cytoplasmic mammalian glutathione S transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. The mu class of these enzymes, to which GSTM1 and 2 belong, functions in the detoxification of electrophilic compounds by conjugation with glutathione. The genes encoding the mu class of enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs and null mutations of this gene have been linked with an increase in a number of cancers.
Cellular localization
Cytoplasmic
References for GSTM1 + GSTM2 peptide (207-217) (ab45671)
ab45671 has not yet been referenced specifically in any publications.
Publishing research using ab45671? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"