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Products:Signal Transduction >> Metabolism >> Mitochondrial
Overview
Product name
GCLC peptide
See all GCLC products (4) ...
Protein description
Synthetic peptide derived from within residues 50 - 150 of Human GCLC.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab41463 - Gamma Glutamylcysteine Synthetase / GCS antibody.
Protein length
637 amino acids
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
Concentration information loading...
Research areas
Cell Biology >> Other Antibodies >> Other Antibodies
Cell Biology >> Other Antibodies >> Oxidative Stress
Signal Transduction >> Metabolism >> Mitochondrial
Applications
Protein info
Pathway
Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.
Involvement in disease
Defects in GCLC are the cause of hemolytic anemia (HAGGSD) [MIM:230450].
Sequence similarities
Belongs to the glutamate--cysteine ligase type 3 family.
Target information above from: UniProt accessionP48506
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for GCLC peptide (ab41462)
ab41462 has not yet been referenced specifically in any publications.
Publishing research using ab41462? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"