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Overview

  • Product nameGCLC peptideSee all GCLC proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 50 - 150 of Human GCLC.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab41463 - Gamma Glutamylcysteine Synthetase / GCS antibody.
  • Protein length637 amino acids

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab41463.

    • Protein info

    • Alternative names
        EC 6.3.2.2Gamma ECSGamma GCS
        Gamma glutamylcysteine synthetaseGamma-ECSGamma-glutamylcysteine synthetaseGCLGCLCGCLMGCSGCS Heavy ChainGLCLGLCLCGLCLRGlutamate cysteine ligase catalytic subunitGlutamate cysteine ligase (gamma glutamylcysteine synthetase) regulatory (30.8kD)Glutamate cysteine ligase catalytic subunitGlutamate cysteine ligase modifier subunitGlutamate cysteine ligase regulatory proteinGlutamate cysteine ligase regulatory subunitGlutamate--cysteine ligase catalytic subunitGSC light chainGSH1_HUMAN
      see all
  • PathwaySulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.
  • Involvement in diseaseDefects in GCLC are the cause of hemolytic anemia (HAGGSD) [MIM:230450].
  • Sequence similaritiesBelongs to the glutamate--cysteine ligase type 3 family.

    • Target information above from: UniProt accession P48506 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for GCLC peptide (ab41462)

    ab41462 has not yet been referenced specifically in any publications.

    Publishing research using ab41462 ? Please let us know so that we can cite the reference in this datasheet

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