Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Reassurance, Refunds & Replacements
If your product does not perform as described on this datasheet, we will refund or replace your product...
Read our guarantee »Overview
Product name
Genistein
Description
Protein tyrosine kinase inhibitor. Anticancer agent.
Biological description
Phytoestrogen found in soy beans. Anticancer agent. Inihibits tyrosine protein kinase and DNA topoisomerase as well as possessing antioxidant and cell cycle inhibitor activity.
Purity
> 99%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Properties
Chemical name
5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
Molecular Weight
270.24
Chemical structure
Molecular formula
C15H10O5
CAS Number
446-72-0
Solubility
Soluble in DMSO to 100 mM
Storage instructions
Store at -20°C (desiccating conditions).
Research areas
Biochemicals >> Pharmacology >> Receptors & Transporters >> Enzyme-Linked Receptors >> Receptor tyrosine kinases >> EGFR
Biochemicals >> Pharmacology >> Enzymes >> Kinase >> Protein Tyrosine Kinase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
References for Genistein (ab120112)
This product has been referenced in:
- Dixon RA & Ferreira D Genistein. Phytochemistry 60:205-11 (2002).Read more (PubMed: 12031439) »
- Sarkar FH & Li Y Mechanisms of cancer chemoprevention by soy isoflavone genistein. Cancer Metastasis Rev 21:265-80 (2002).Read more (PubMed: 12549765) »
See all 3 publications for this product
Publishing research using ab120112? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"