Glucose 6 Phosphate Dehydrogenase antibody (Biotin) (ab20606)

Product Name 

Glucose 6 Phosphate Dehydrogenase antibody (Biotin)

Product type 

Primary antibodies

Description 

Goat polyclonal to Glucose 6 Phosphate Dehydrogenase (Biotin)

Immunogen 

Glucose 6 Phosphate Dehydrogenase (Leuconostoc mesenteroides).

Species Reactivity 

Reacts with Leuconostoc mesenteroides.
Not yet tested in other species.

Specificity 

This antibody is specific to purified and partially purified Glucose 6 Phosphate Dehydrogenase (Leuconostoc mesenteroides).

Tested applications 
(see key)

ELISA

Abreviews 

Customer reviews (see key)

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Application notes 
(see key)

Recommended dilutions
ELISA: 1/1000 - 1/5000.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cytoplasmic

Research areas 

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of carbohydrates
Cardiovascular >> Heart >> Cardiac metabolism
Cardiovascular >> Atherosclerosis >> Diabetes associated
Signal Transduction >> Metabolism >> Energy Metabolism

Relevance 

Glucose 6 Phosphate Dehydrogenase (G6PD) produces pentose sugars for nucleic acid synthesis and is the main producer of NADPH reducing power. Catalytic activity: D glucose 6 phosphate + NADP(+) = D glucono 1,5 lactone 6 phosphate + NADPH. Defects in G6PD are the cause of chronic non spherocytic haemolytic anemia (CNSHA). G6PD deficiency is the most common human enzyme deficiency; one benefit of having G6PD deficiency is that it confers a resistance to malaria.

Raised in 

Goat

Clonality 

Polyclonal

Isotype 

IgG

Storage buffer 

Preservative: 0.01% Sodium Azide
Constituents: PBS, pH 7.2

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Purification notes 

Purified from monospecific antiserum by delipidation, fractionation and ion exchange chromatography.

Form 

Liquid

Conjugation 

Biotin

Concentration 

10.000 mg/ml

Storage instructions 

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C (add glycerol to a final volume of 50% for extra stability). Avoid repeated freeze / thaw cycles.

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