Anti-Glucose 6 Phosphate Dehydrogenase antibody (ab80362)

Overview

• Product nameAnti-Glucose 6 Phosphate Dehydrogenase antibodySee all Glucose 6 Phosphate Dehydrogenase primary antibodies ...
• Description
  Rabbit polyclonal to Glucose 6 Phosphate Dehydrogenase
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant human Glucose 6 Phosphate Dehydrogenase protein.

• Positive controlInduced Glucose 6 Phosphate Dehydrogenase E.Coli total lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: Whole serum
• PurityWhole antiserum
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Metabolism
  • Types of disease
  • Diabetes

  • Metabolism
  • Types of disease
  • Heart disease

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Cardiovascular
  • Heart
  • Cardiac metabolism

  • Cardiovascular
  • Atherosclerosis
  • Diabetes associated

Applications

Target

• FunctionProduces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power.
• Tissue specificityIsoform Long is found in lymphoblasts, granulocytes and sperm.
• PathwayCarbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
• Involvement in diseaseChronic non-spherocytic hemolytic anemia (CNSHA) [MIM:305900]: Deficiency of G6PD is associated with hemolytic anemia in two different situations. First, in areas in which malaria has been endemic, G6PD-deficiency alleles have reached high frequencies (1% to 50%) and deficient individuals, though essentially asymptomatic in the steady state, have a high risk of acute hemolytic attacks. Secondly, sporadic cases of G6PD deficiency occur at a very low frequencies, and they usually present a more severe phenotype. Several types of CNSHA are recognized. Class-I variants are associated with severe NSHA; class-II have an activity <10% of normal; class-III have an activity of 10% to 60% of normal; class-IV have near normal activity. Note=The disease is caused by mutations affecting the gene represented in this entry.
• Sequence similaritiesBelongs to the glucose-6-phosphate dehydrogenase family.

Target information above from: UniProt accession P11413 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 2539 Human
  • Omim: 305900 Human
  • SwissProt: P11413 Human
  • Unigene: 461047 Human
  • Unigene: 684904 Human

• Alternative names
  G6PD antibodyG6PD_HUMAN antibodyG6PD1 antibody

  G6pdx antibodyGlucose 6 phosphate 1 dehydrogenase antibodyGlucose 6 phosphate dehydrogenase antibodyGlucose 6 phosphate dehydrogenase, G6PD antibodyGlucose-6-phosphate 1-dehydrogenase antibodyMET19 antibodyPOS10 antibodyZwf1p antibody

  see all

Anti-Glucose 6 Phosphate Dehydrogenase antibody images

• 

  Western blot - Glucose 6 Phosphate Dehydrogenase antibody (ab80362)
  Anti-Glucose 6 Phosphate Dehydrogenase antibody (ab80362) at 1/3000 dilution + Induced Glucose 6 Phosphate Dehydrogenase E.Coli total lysate
  
  Secondary
  goat anti-rabbit HRP
  developed using the ECL technique
  
  Predicted band size : 59 kDa
  Observed band size : 59 kDa
  
  
  Exposure time : 1 minute