Anti-Glucose 6 Phosphate Dehydrogenase antibody (ab80362)

Overview

  • Product name
    Anti-Glucose 6 Phosphate Dehydrogenase antibody
    See all Glucose 6 Phosphate Dehydrogenase primary antibodies
  • Description
    Rabbit polyclonal to Glucose 6 Phosphate Dehydrogenase
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant human Glucose 6 Phosphate Dehydrogenase protein.

  • Positive control
    • Induced Glucose 6 Phosphate Dehydrogenase E.Coli total lysate.

Applications

Our Abpromise guarantee covers the use of ab80362 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notes
    WB: 1/400 - 1/3000 (dependent on cell lysate or recombinant protein). Detects a band of approximately 59 kDa (predicted molecular weight: 59 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.
    • Tissue specificity
      Isoform Long is found in lymphoblasts, granulocytes and sperm.
    • Pathway
      Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.
    • Involvement in disease
      Anemia, non-spherocytic hemolytic, due to G6PD deficiency
    • Sequence similarities
      Belongs to the glucose-6-phosphate dehydrogenase family.
    • Post-translational
      modifications
      Acetylated by ELP3 at Lys-403; acetylation inhibits its homodimerization and enzyme activity. Deacetylated by SIRT2 at Lys-403; deacetylation stimulates its enzyme activity.
    • Information by UniProt
    • Database links
    • Alternative names
      • G6PD antibody
      • G6PD_HUMAN antibody
      • G6PD1 antibody
      • G6pdx antibody
      • Glucose 6 phosphate 1 dehydrogenase antibody
      • Glucose 6 phosphate dehydrogenase antibody
      • Glucose 6 phosphate dehydrogenase, G6PD antibody
      • Glucose-6-phosphate 1-dehydrogenase antibody
      • MET19 antibody
      • POS10 antibody
      • Zwf1p antibody
      see all

    Images

    • Anti-Glucose 6 Phosphate Dehydrogenase antibody (ab80362) at 1/3000 dilution + Induced Glucose 6 Phosphate Dehydrogenase E.Coli total lysate

      Secondary
      goat anti-rabbit HRP
      Developed using the ECL technique

      Predicted band size : 59 kDa
      Observed band size : 59 kDa


      Exposure time : 1 minute

    References

    ab80362 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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