You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Overview

  • Product nameEAAT2 peptideSee all EAAT2 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 550 to the C-terminus of Human Glutamate Transporter 1 (EEAT2).(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab41621 - Glutamate Transporter 1 antibody.
  • Protein length573 amino acids

    • Properties

  • Purity70 - 90% by HPLC
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab41752 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Blocking
  • Application notesBL: Use at a concentration of 1 µg/ml.
    This peptide can be used with studies using ab41621


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        EAA2_HUMANEAAT2Excitatory amino acid transporter 2
        Excitotoxic amino acid transporter 2Glial high affinity glutamate transporterGLT 1GLT1Glutamate aspartate transporter IIGlutamate/aspartate transporter IISLC1A2Sodium dependent glutamate aspartate transporter 2Sodium-dependent glutamate/aspartate transporter 2Solute carrier family 1 glial high affinity glutamate transporter member 2Solute carrier family 1 member 2
      see all
  • FunctionTransports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
  • Sequence similaritiesBelongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A2 subfamily.
  • Post-translational
    modifications    Glycosylated.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession P43004 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for EAAT2 peptide (ab41752)

    This product has been referenced in:
    • Potapenko ES  et al. Altered astrocyte glutamate transporter regulation of hypothalamic neurosecretory neurons in heart failure rats. Am J Physiol Regul Integr Comp Physiol 303:R291-300 (2012). Read more (PubMed: 22696576) »

    See 1 Publication for this product

    Publishing research using ab41752 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab41752 Submit a Question for ab41752

    There are currently no Abreviews or Questions for ab41752.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"