Anti-Glutathione Peroxidase 3 antibody (ab59524)
Overview
- Product nameAnti-Glutathione Peroxidase 3 antibodySee all Glutathione Peroxidase 3 primary antibodies ...
- DescriptionGoat polyclonal to Glutathione Peroxidase 3
- Specificityab59524 may crossreact with epididymis-specific Glutathione peroxidase 5(GPX5) and olfactory epithelium-speciific Glutathione peroxidase 6 (GPX6).
- Tested applicationsWB more details
- Species reactivityReacts with: Mouse, Rat
Predicted to work with: Cow, Dog, Human - Immunogen
Synthetic peptide: C-NQFGKQEPGENSE, corresponding to internal sequence amino acids 102-114 of Human Glutathione Peroxidase 3
- Positive controlMouse Heart, Kidney and Liver lysates.
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 -
Concentration information loading... - PurityImmunogen affinity purified
- Purification notesab59524 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
- Clonality Polyclonal
- IsotypeIgG
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Research Areas
Applications
Our Abpromise guarantee covers the use of ab59524 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB |
Peptide ELISA: antibody detection limit dilution 1:1000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionProtects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
- Tissue specificitySecreted in plasma.
- Sequence similaritiesBelongs to the glutathione peroxidase family.
- Post-translational
modificationsThe N-terminus is blocked. - Cellular localizationSecreted.
-
Database links
- Entrez Gene: 2878 Human
- Entrez Gene: 14778 Mouse
- Entrez Gene: 64317 Rat
- Omim: 138321 Human
- SwissProt: P22352 Human
- SwissProt: P46412 Mouse
- SwissProt: P23764 Rat
- Unigene: 386793 Human
- Unigene: 200916 Mouse
- Unigene: 108074 Rat
see all
Target information above from: UniProt accession
P22352
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
.
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Alternative names
- Extracellular glutathione peroxidase antibodyGlutathione peroxidase 3 (plasma) antibodyGlutathione peroxidase 3 antibody
- GPX 3 antibodyGPx P antibodyGPx-3 antibodyGPx-P antibodyGPX3 antibodyGPX3_HUMAN antibodyGPXP antibodyGSHPx 3 antibodyGSHPx P antibodyGSHPx-3 antibodyGSHPx-P antibodyPlasma glutathione peroxidase 3 antibodyPlasma glutathione peroxidase antibody
see all
Anti-Glutathione Peroxidase 3 antibody images
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Western blot - Glutathione Peroxidase 3 antibody (ab59524)Anti-Glutathione Peroxidase 3 antibody (ab59524) at 1 µg/ml + Mouse Heart lysate in RIPA buffer at 35 µg
Predicted band size : 25 kDa
Observed band size : 28 kDa (why is the actual band size different from the predicted?)
References for Anti-Glutathione Peroxidase 3 antibody (ab59524)
This product has been referenced in:
- Lubieniecka JM et al. Biomarkers for severity of spinal cord injury in the cerebrospinal fluid of rats. PLoS One 6:e19247 (2011). WB ; Rat . Read more (PubMed: 21559420) »
