Anti-Glutathione Reductase antibody (ab137513)
Key features and details
- Rabbit polyclonal to Glutathione Reductase
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
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- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Glutathione Reductase antibody
See all Glutathione Reductase primary antibodies -
Description
Rabbit polyclonal to Glutathione Reductase -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 164-403 of Human Glutathione Reductase (UniProt ID: P00390).
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Positive control
- A549, HeLa, HepG2, HCT116 and Mouse brain whole cell lysates.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137513 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 56 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 56 kDa. |
Target
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Function
Maintains high levels of reduced glutathione in the cytosol. -
Sequence similarities
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. -
Domain
Each subunit can be divided into 4 domains that are consecutive along the polypeptide chain. Domains 1 and 2 bind FAD and NADPH, respectively. Domain 4 forms the interface. -
Cellular localization
Cytoplasm and Mitochondrion. - Information by UniProt
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Database links
- Entrez Gene: 2936 Human
- Entrez Gene: 14782 Mouse
- Entrez Gene: 116686 Rat
- Omim: 138300 Human
- SwissProt: P00390 Human
- SwissProt: P47791 Mouse
- SwissProt: P70619 Rat
- Unigene: 271510 Human
see all -
Alternative names
- GLR1 antibody
- GLUR antibody
- Glutathione reductase antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab137513 has been referenced in 3 publications.
- Nakamura Y et al. Placental Mitochondria Therapy for Cerebral Ischemia-Reperfusion Injury in Mice. Stroke 51:3142-3146 (2020). PubMed: 32819193
- Tarpey MD et al. Induced in vivo knockdown of the Brca1 gene in skeletal muscle results in skeletal muscle weakness. J Physiol 597:869-887 (2019). PubMed: 30556208
- Gu Y et al. Involvement of Kruppel-like factor 9 in bleomycin-induced pulmonary toxicity. Mol Med Rep 12:5262-6 (2015). PubMed: 26133229