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Read our guarantee »Products:Neuroscience >> Neurotransmitter >> Amino Acids >> Glycine
Anti-Glycine antibody
See all Glycine products (2) ...
Rabbit polyclonal to Glycine
This antibody targets conjugated glycine. Using a conjugate glycine-Protein Carrier (Pc), antibody specificity was performed with an ELISA test by competition experiments with the following compounds: Glycine-G-(Pc) = 1 ß-Alanine-G-(Pc) = 1/100 GABA-G-(Pc) = 1/500 Taurine-G-(Pc) = 1/1,000 Aspartate-G-(Pc) = 1/20,000 Glutamate-G-(Pc) = 1/>20,000 Glycine = 1/>50,000 G = Glutaraldehyde § Glycine-G-(Pc) concentration/unconjugated or conjugated amino acids concentration at half displacement.
ELISA, ICC, WBmore details
not applicable
Synthetic glycine conjugated to protein carrier.
Liquid
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Preservative: None
Constituents: 50% Glycerol, ddH20
Whole antiserum
Antiserum previously preabsorbed on protein carriers and purified. Antisera antibody was lyophilized and then reconstituted in buffer.
Polyclonal
IgG
Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurotransmitter >> Amino Acids >> Glycine
Our Abpromise guarantee covers the use of ab37087 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: 1/1000 - 1/5000.
ICC: 1/1000 - 1/5000. (Not recommended for use with formaldehyde).
WB: 1/1000 - 1/2000.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Defects in GLDC are a cause of nonketotic hyperglycinemia (NKH), also known as glycine encephalopathy (GCE). NKH is an autosomal recessive disease characterized by accumulation of a large amount of glycine in body fluid and by severe neurological symptoms. The degredation of glycine is catalised by the glycine cleavage system. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; carbondioxide is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. The glycine cleavage system is composed of four proteins: P, T, L and H.
ab37087 has not yet been referenced specifically in any publications.
Publishing research using ab37087? Please let us know so that we can cite the reference in this datasheet
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