Anti-Glycogen synthase 1 antibody [3A7] (ab110027)

Overview

• Product nameAnti-Glycogen synthase 1 antibody [3A7]See all Glycogen synthase 1 primary antibodies ...
• Description
  Mouse monoclonal [3A7] to Glycogen synthase 1
• Tested applicationsWB, Flow Cyt, ELISA, ICC/IF more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Purified recombinant fragment of Human Glycogen synthase 1 expressed in E. Coli.

• Positive controlHEK393 cell lysate, K562 cells

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPreservative: 0.03% Sodium Azide
  Constituents: Ascites
• Concentration information loading...
• PurityAscites
• Clonality Monoclonal
• Clone number3A7
• IsotypeIgG1
• Research Areas
  • Metabolism
  • Types of disease
  • Heart disease

  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Types of disease
  • Diabetes

  • Metabolism
  • Types of disease
  • Obesity

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Cardiovascular
  • Atherosclerosis
  • Diabetes associated

Applications

Target

• FunctionTransfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
• PathwayGlycan biosynthesis; glycogen biosynthesis.
• Involvement in diseaseDefects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also known as muscle glycogen synthase deficiency. GSD0b is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.
• Sequence similaritiesBelongs to the glycosyltransferase 3 family.

Target information above from: UniProt accession P13807 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 2997 Human
  • Entrez Gene: 2997 Human
  • Entrez Gene: 2997 Human
  • Omim: 138570 Human
  • SwissProt: P13807 Human
  • SwissProt: P13807 Human
  • SwissProt: P13807 Human
  • Unigene: 386225 Human

• Alternative names
  Glycogen [starch] synthase antibodyGlycogen synthase 1 (muscle) antibodyGlycogen synthase 1 antibody

  GSY antibodyGYS antibodyGys1 antibodyGYS1_HUMAN antibodymuscle antibody

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Anti-Glycogen synthase 1 antibody [3A7] images

• 

  Western blot - Glycogen synthase 1 antibody [3A7] (ab110027)
  Anti-Glycogen synthase 1 antibody [3A7] (ab110027) at 1/500 dilution + HEK393 cell lysate
  
  Predicted band size : 84 kDa
  
• 

  Flow Cytometry - Glycogen synthase 1 antibody [3A7] (ab110027)
  Flow cytometric analysis of K562 cells using ab110027 (green) and negative control (purple).
• 

  ELISA - Glycogen synthase 1 antibody [3A7] (ab110027)
  The proposed dilution of ab110027 for ELISA is 1/10000.