You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Anti-Glycogen synthase 1 antibody [EP817Y] (ab40810)

CodeSizePriceAbpointsAvailability
    
Add to basket
 

  • -

  •   
  •   
  •   

  •  

  •  
  •  

  •  

  •  
Updating...

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »

Overview

Product name

Anti-Glycogen synthase 1 antibody [EP817Y]
See all Glycogen synthase 1 products (9) ...

Description

Rabbit monoclonal [EP817Y] to Glycogen synthase 1

Tested applications

IHC-P, WB, ICC/IF, Flow Cyt, IPmore details

Cross reactivity

Reacts with

Mouse, Rat, Human

Immunogen

Synthetic peptide corresponding to residues in the C-terminus of Human Glycogen Synthase.

Positive control

Hela cell lysate.

General notes

Produced under U.S. Patent No. 5,675,063.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Monoclonal

Clone number

EP817Y

Isotype

IgG

Research areas

Metabolism >> Types of disease >> Heart disease
Metabolism >> Types of disease >> Cancer
Metabolism >> Types of disease >> Diabetes
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Energy transfer pathways >> Energy Metabolism
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Carbohydrate metabolism
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of carbohydrates
Cardiovascular >> Atherosclerosis >> Diabetes associated
Signal Transduction >> Metabolism >> Energy Metabolism

  • Western blot - Glycogen synthase 1 antibody [EP817Y] (ab40810)Western blot - Glycogen synthase 1 antibody [EP817Y] (ab40810) image (enlarge)

  • Immunocytochemistry/ Immunofluorescence - Glycogen synthase 1 antibody [EP817Y] (ab40810)Immunocytochemistry/ Immunofluorescence - Glycogen synthase 1 antibody [EP817Y] (ab40810) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab40810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 1 Image

    IHC-P

     IHC-P: 1/250 - 1/500.

    IHC-P: 1/250 - 1/500.

  • ShowHide1 Image

    WB

     WB: 1/10000 - 1/50000. D...Read more →

    WB: 1/10000 - 1/50000. Detects a band of approximately 85 kDa (predicted molecular weight: 81 kDa).

  • 1 Image

    ICC/IF

     ICC/IF: 1/250 - 1/500.

    ICC/IF: 1/250 - 1/500.

  • Flow Cyt

     Flow Cyt: 1/50.

    Flow Cyt: 1/50.

  • IP

     IP: 1/50.

    IP: 1/50.

Target

Function

Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

Pathway

Glycan biosynthesis; glycogen biosynthesis.

Involvement in disease

Defects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also known as muscle glycogen synthase deficiency. GSD0b is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.

Sequence similarities

Belongs to the glycosyltransferase 3 family.

Target information above from: UniProt accessionP13807 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • muscle antibody
  • EC 2.4.1.11 antibody
  • Glycogen [starch] synthase antibody
  • Glycogen antibody
  • Glycogen synthase 1 (muscle) antibody
  • Glycogen synthase 1 antibody
  • Glycogen synthase1 antibody
  • GSY antibody
  • GYS 1 antibody
  • GYS antibody
  • GYS1 antibody
  • GYS1_HUMAN antibody
  • Starchsynthase muscle antibody
  • UDP glucose glycogen glucosyltransferase antibody
see all

Database links

see all

Anti-Glycogen synthase 1 antibody [EP817Y] images:

  Western blot - Glycogen synthase 1 antibody [EP817Y] (ab40810)

Western blot - Glycogen synthase 1 antibody [EP817Y] (ab40810)

Anti-Glycogen synthase 1 antibody [EP817Y] (ab40810) at 1/50000 dilution + HeLa cell lysate at 10 µg

Predicted band size : 81 kDa
Observed band size : 85 kDa (why is the actual band size different from the predicted?)

  Immunocytochemistry/ Immunofluorescence - Glycogen synthase 1 antibody [EP817Y] (ab40810)

Immunocytochemistry/ Immunofluorescence - Glycogen synthase 1 antibody [EP817Y] (ab40810)

ab40810 at a 1:250 dilution staining Hela cells using anti-Glycogen Synthase 1 RabMAb.

References for Anti-Glycogen synthase 1 antibody [EP817Y] (ab40810)

This product has been referenced in:

  • Cameron JM  et al. Identification of a novel mutation in GYS1 (muscle-specific glycogen synthase) resulting in sudden cardiac death, that is diagnosable from skin fibroblasts. Mol Genet Metab 98:378-82 (2009). WB; Human.Read more (PubMed: 19699667) »

See 1 publication for this product

Publishing research using ab40810? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"