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Overview

  • Product nameGranzyme A peptideSee all Granzyme A proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 200 to the C-terminus of Human Granzyme A.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab73420 - Granzyme A antibody.
  • Protein length262 amino acids

    • Properties

  • Purity70 - 90% by HPLC
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab73420.

    • Protein info

    • Alternative names
        CTL tryptaseCTLA3Cytolytic t cell and natural killer cell specific trypsin like serine protease
        Cytotoxic T lymphocyte associated serine esterase 3Cytotoxic T lymphocyte proteinase 1Cytotoxic T-lymphocyte proteinase 1Fragmentin 1Fragmentin-1GRAA_HUMANGranzyme 1 cytotoxic T lymphocyte associated serine esterase 3Granzyme AGranzyme A (Cytotoxic T lymphocyte associated serine esterase 3; Hanukah factor serine protease)Granzyme A (granzyme 1, cytotoxic T lymphocyte associated serine esterase 3)Granzyme A precursorGranzyme-1GZMAH factorHanukah factor serine proteaseHanukkah factorHFHFSPTSP1
      see all
  • FunctionThis enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Involved in apoptosis.
  • Sequence similaritiesBelongs to the peptidase S1 family. Granzyme subfamily.
    Contains 1 peptidase S1 domain.
  • Cellular localizationSecreted. Cytoplasmic granule.

    • Target information above from: UniProt accession P12544 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for Granzyme A peptide (ab90219)

    ab90219 has not yet been referenced specifically in any publications.

    Publishing research using ab90219 ? Please let us know so that we can cite the reference in this datasheet

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