Anti-Grp75 antibody [10D7] (ab114024)

Overview

• Product nameAnti-Grp75 antibody [10D7]See all Grp75 primary antibodies ...
• Description
  Mouse monoclonal [10D7] to Grp75
• Tested applicationsFlow Cyt, ICC/IF more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length Human Grp75 produced in HEK293T cells (NP_004125)

• Positive controlICC/IF: COS7 cells transiently transfected Flow Cyt: Transfected HEK293T cells

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferpH: 7.30
  Preservative: 0.02% Sodium azide
  Constituents: PBS, 50% Glycerol, 1% BSA
• Concentration information loading...
• PurityIgG fraction
• Purification notesPurified from mouse ascites fluids by affinity chromatography
• Clonality Monoclonal
• Clone number10D7
• IsotypeIgG1
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial markers

  • Metabolism
  • Pathways and Processes
  • Mitochondrial Metabolism
  • Mitochondrial Biogenesis

  • Cancer
  • Tumor biomarkers
  • Other

  • Cancer
  • Cell cycle
  • Cell division

  • Signal Transduction
  • Protein Trafficking
  • Chaperones
  • Heat Shock Proteins

Applications

Target

• FunctionImplicated in the control of cell proliferation and cellular aging. May also act as a chaperone.
• Sequence similaritiesBelongs to the heat shock protein 70 family.
• Post-translational
  modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
• Cellular localizationMitochondrion.

Target information above from: UniProt accession P38646 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 3313 Human
  • Omim: 600548 Human
  • SwissProt: P38646 Human
  • Unigene: 184233 Human

• Alternative names
  75 kDa glucose regulated protein antibody75 kDa glucose-regulated protein antibodyCSA antibody

  Glucose Regulated Protein antibodyGrp 75 antibodyGRP-75 antibodyGRP75 antibodyGRP75_HUMAN antibodyHeat shock 70 kDa protein 9 antibodyHeat shock 70kD protein 9 antibodyheat shock 70kDa protein 9 antibodyHeat shock 70kDa protein 9B antibodyHeat shock protein 74 kDa A antibodyHeat shock protein A antibodyHeat shock protein cognate 74 antibodyHsc74 antibodyHsp74 antibodyHsp74a antibodyHSPA9 antibodyHspa9a antibodyHSPA9B antibodyMGC4500 antibodymitochondrial antibodyMortalin 2 antibodyMortalin antibodyMortalin perinuclear antibodyMortalin2 antibodyMOT 2 antibodyMOT antibodyMOT2 antibodyMthsp70 antibodyp66 mortalin antibodyP66 MOT antibodyPBP74 antibodyPeptide binding protein 74 antibodyPeptide-binding protein 74 antibodyStress 70 protein mitochondrial antibodyStress 70 protein mitochondrial precursor antibodyStress-70 protein antibody

  see all

Anti-Grp75 antibody [10D7] images

• 

  Immunocytochemistry/ Immunofluorescence - Anti-Grp75 antibody [10D7] (ab114024)
  Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HSPA9, using ab114024 at 1/100
• 

  Flow Cytometry - Anti-Grp75 antibody [10D7] (ab114024)
  HEK293T cells transfected with either pCMV6-ENTRY HSPA9 (Red) or empty vector control plasmid (Blue) were immunostained with ab114024 at 1/100 and then analyzed by flow cytometry.