Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Signal Transduction >> Growth Factors/Hormones >> Hormones
Overview
Product name
Anti-H6PD antibody
See all H6PD products (4) ...
Description
Mouse polyclonal to H6PD
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Full length human H6PD protein (AAH81559.1, 1 a.a. ~ 791 a.a)
Positive control
Human liver tissue lysate. H6PD transfected 293T cell lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Neuroscience >> Neurology process >> Metabolism
Signal Transduction >> Metabolism >> Energy Metabolism
Signal Transduction >> Growth Factors/Hormones >> Hormones
Applications
Show applications key
Our Abpromise guarantee covers the use of ab69894 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: 1/500 - 1/1000.Detects a band of approximately 89 kDa (predicted molecular weight: 89 kDa).
Target
Function
Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates.
Tissue specificity
Present in most tissues examined, strongest in liver.
Involvement in disease
Defects in H6PD are a cause of cortisone reductase deficiency (CRD) [MIM:604931]. In CRD, activation of cortisone to cortisol does not occur, resulting in adrenocorticotropin-mediated androgen excess and a phenotype resembling polycystic ovary syndrome (PCOS).
Sequence similarities
In the N-terminal section; belongs to the glucose-6-phosphate dehydrogenase family.
In the C-terminal section; belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Cellular localization
Endoplasmic reticulum lumen. Microsomes, endoplasmic reticulum lumen.
Target information above from: UniProt accessionO95479
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 6 phosphogluconolactonase antibody
- 6-phosphogluconolactonase antibody
- 6PGL antibody
see all
Database links
- Entrez Gene: 25796 Human
- Entrez Gene: 9563 Human
- Omim: 138090 Human
- SwissProt: O95336 Human
- SwissProt: O95479 Human
- Unigene: 463511 Human
- Unigene: 466165 Human
Anti-H6PD antibody images:
Western blot - H6PD antibody (ab69894)
Anti-H6PD antibody (ab69894) at 1/500 dilution + human liver tissue lysate at 25 µg
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size : 89 kDa
Observed band size : 89 kDa
Western blot - H6PD antibody (ab69894)
All lanes : Anti-H6PD antibody (ab69894) at 1/500 dilution
Lane 1 : H6PD transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size : 89 kDa
Observed band size : 89 kDa
References for Anti-H6PD antibody (ab69894)
ab69894 has not yet been referenced specifically in any publications.
Publishing research using ab69894? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"