HA14-1, Bcl-2 inhibitor. BH-3 mimetic. (ab141306)
Key features and details
- Cell permeable Bcl-2 inhibitor. BH-3 mimetic.
- CAS Number: 65673-63-4
- Soluble in DMSO to 100 mM and in ethanol to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
HA14-1, Bcl-2 inhibitor. BH-3 mimetic. -
Description
Cell permeable Bcl-2 inhibitor. BH-3 mimetic. -
Biological description
Cell permeable Bcl-2 inhibitor. BH-3 mimetic. Disrupts Bax and Bcl-2 interactions. Apoptotic anticancer agent.
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CAS Number
65673-63-4 -
Chemical structure
Properties
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Chemical name
2-Amino-6-bromo-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester -
Molecular weight
409.23 -
Molecular formula
C17H17BrN2O5 -
PubChem identifier
3549 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in DMSO to 100 mM and in ethanol to 100 mM -
Handling
Unstable; make up solutions fresh and use immediately.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C(OCC)C(C#N)C1c2cc(Br)ccc2OC(N)=C1C(=O)OCC -
Source
Synthetic
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Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (0)
ab141306 has not yet been referenced specifically in any publications.