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Anti-HAAO antibody (ab83242)

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Overview

Product name

Anti-HAAO antibody
See all HAAO products (4) ...

Description

Rabbit polyclonal to HAAO

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Cow, Zebrafish

Immunogen

Synthetic peptide corresponding to a region within the N terminal amino acids 71-120 (HRDVVIRQGE IFLLPARVPH SPQRFANTVG LVVERRRLET ELDGLRYYVG) of Human HAAO (NP_036337).

HRDVVIRQGE IFLLPARVPH SPQRFANTVG LVVERRRLET ELDGLRYYVG

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

293T cell lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurology process >> Neurodegenerative disease >> Huntington's disease

  • Western blot - HAAO antibody (ab83242)Western blot - HAAO antibody (ab83242) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab83242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

ELISA: Use at an assay dependent dilution. ELISA titre using peptide based assay 1/312500.
WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 33 kDa).


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Function

Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.

Sequence similarities

Belongs to the 3-HAO family.

Cellular localization

Cytoplasm.

Target information above from: UniProt accessionP46952 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Form

There are 2 isoforms produced by alternative splicing.

Alternative names

  • 3 HAO antibody
  • 3 hydroxyanthranilate 3 4 dioxygenase antibody
  • 3 hydroxyanthranilate dioxygenase antibody
  • 3 hydroxyanthranilate oxygenase antibody
  • 3 hydroxyanthranilic acid dioxygenase antibody
  • 3-HAO antibody
  • 3-hydroxyanthranilate 3,4-dioxygenase antibody
  • 3-hydroxyanthranilate oxygenase antibody
  • 3-hydroxyanthranilic acid dioxygenase antibody
  • 3HAO_HUMAN antibody
  • haao antibody
  • HAD antibody
  • HAO antibody
see all

Database links

see all

Anti-HAAO antibody images:

  Western blot - HAAO antibody (ab83242)

Western blot - HAAO antibody (ab83242)

Anti-HAAO antibody (ab83242) at 1 µg/ml + 293T cell lysate at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 33 kDa
Observed band size : 33 kDa


Gel concentration 12%

References for Anti-HAAO antibody (ab83242)

ab83242 has not yet been referenced specifically in any publications.

Publishing research using ab83242? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"