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ELISA - HABP2 antibody (ab55229)
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Product Name
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HABP2 antibody
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See all HABP2 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to HABP2
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Immunogen
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Recombinant fragment: GNKCQKVQNT CKDNPCGRGQ CLITQSPPYY RCVCKHPYTG PSCSQVVPVC RPNPCQNGAT CSRHKRRSKF TCACPDQFKG KFCEIGSDDC YVGDGYSYRG , corresponding to amino acids 105-205 of Human HABP2
BLAST 'GNKCQKVQNT CKDNPCGRGQ CLITQSPPYY RCVCKHPYTG PSCSQVVPVC RPNPCQNGAT CSRHKRRSKF TCACPDQFKG KFCEIGSDDC YVGDGYSYRG ' with  or 
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Reacts with
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RecFrag
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Predicted to react
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Hu
(Due to sequence homology)
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Tested applications
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ELISA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted. Note: Secreted as an inactive single chain precursor and is then activated to a heterodimeric form.
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Research areas
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Cardiovascular >> Blood >> Serum Proteins
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Relevance
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Hyaluronan binding protein 2 (HABP2) is an extracellular serine protease which binds hyaluronic acid. It is involved in cell adhesion. The protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. Two transcript variants utilizing alternative polyA sites exist for this gene.
HABP2 cleaves the alpha chain at multiple sites and the beta chain between 'Lys-53' and 'Lys-54' but not the gamma chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro urokinase) to the active two chain form. It also activates coagulation factor VII.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this HABP2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for HABP2 antibody images, references, products related to ab55229 and other tools.
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HABP2 antibody images:
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 ELISA - HABP2 antibody (ab55229)
ab55229, staining HABP2 by Elisa. The detection limit for recombinant tagged HABP2 is approximately 1ng/ml as a capture antibody.
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Search PubMed (MEDLINE) for references to HABP2
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HABP2 antibody - more information
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Customer reviews (feedback) regarding HABP2 antibody |
Customer FAQs regarding HABP2 antibody |
Protocols for HABP2 antibody |
Price and availability of products related to HABP2 antibody |
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HABP2 antibody - related products:
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HABP2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about HABP2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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