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Western blot - HAND2 antibody (ab10131)
Western blot - HAND2 antibody (ab10131)
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Product Name 

HAND2 antibody

 

See all HAND2 antibodies (3)...

Product type 

Primary antibodies

Description 

Rabbit polyclonal to HAND2

Immunogen 

Synthetic peptide conjugated to KLH, corresponding to a region between amino acids 190-204 of Human HAND2.

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
WB: 1/1000. Detects a band of approximately 24 kDa (predicted molecular weight: 26 kDa).
ELISA: positive result with immunising peptide.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

HeLa whole cell lysate.

Cellular localization 

Nuclear

Research areas 

Cardiovascular >> Heart >> Hypertrophy >> Transcription factors
Cardiovascular >> Heart >> Cardiogenesis >> Transcription factors/regulators
Neuroscience >> Neurology process >> Neurogenesis
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH

Relevance 

The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

 

Alternative names HAND2 antibody (ab10131)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

9464    (Human)

Omim

    

602407    (Human)

SwissProt

    

P61296    (Human)

Unigene

    

388245    (Human)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Protein A purified

Storage buffer 

Preservative: None
Constituents: PBS, Sucrose

Form 

Liquid

Concentration 

Batch dependent within range: 1.00 - 2.00 mg/ml

Concentration of lot no.     is  

Concentration not available for this lot.

Find concentration of your lot :

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this HAND2 antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for HAND2 antibody images, references, products related to ab10131 and other tools.

 

HAND2 antibody images:

Product image  Western blot - HAND2 antibody (ab10131)

Western blot - HAND2 antibody (ab10131)



Predicted band size : 26 kDa


ab10131 at 1/1000 dilution staining approximately 24kDa band of human HAND2 in HeLa whole cell lysate by Western blot (ECL).

 
 

Search PubMed (MEDLINE) for references to HAND2

 

HAND2 antibody - more information

Customer reviews (feedback) regarding HAND2 antibody

Customer FAQs regarding HAND2 antibody

Protocols for HAND2 antibody

Price and availability of products related to HAND2 antibody

 

HAND2 antibody - related products:

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Other HAND2 Antibodies

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HAND2 antibody - other tools:

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