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Western blot - HAND2 antibody (ab56590)
(enlarge)
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Product Name
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HAND2 antibody
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See all HAND2 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to HAND2
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Immunogen
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Recombinant fragment: LSKIKTLRLA TSYIAYLMDL LAKDDQNGEA EAFKAEIKKT DVKEEKRKKE LNEILKSTVS SNDKKTKGRT GWPQHVWALE LK, corresponding to amino acids 135-217 of Human HAND2
BLAST 'LSKIKTLRLA TSYIAYLMDL LAKDDQNGEA EAFKAEIKKT DVKEEKRKKE LNEILKSTVS SNDKKTKGRT GWPQHVWALE ' with  or 
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Cardiovascular >> Heart >> Hypertrophy >> Transcription factors
Cardiovascular >> Heart >> Cardiogenesis >> Transcription factors/regulators
Neuroscience >> Neurology process >> Neurogenesis
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
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Relevance
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The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this HAND2 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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HAND2 antibody images:
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 Western blot - HAND2 antibody (ab56590)
Western blot against tagged recombinant protein immunogen using ab56590 HAND2 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa
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Search PubMed (MEDLINE) for references to HAND2
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HAND2 antibody - more information
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Customer reviews (feedback) regarding HAND2 antibody |
Customer FAQs regarding HAND2 antibody |
Protocols for HAND2 antibody |
Price and availability of products related to HAND2 antibody |
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HAND2 antibody - other tools:
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Contact Abcam with a Technical Enquiry about HAND2 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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