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Products:Immunology >> Immune System Diseases >> Autoimmune
Overview
Product name
Anti-HARS antibody
See all HARS products (5) ...
Description
Mouse monoclonal to HARS
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant fragment: MAERAALEEL VKLQGERVRG LKQQKASAEL IEEEVAKLLK LKAQLGPDES KQKFVLKTPK GTRDYSPRQM AVREKVFDVI IRCFKRHGAE VIDTPV, corresponding to amino acids 1-97 of Human HARS
MAERAALEEL VKLQGERVRG LKQQKASAEL IEEEVAKLLK LKAQLGPDES KQKFVLKTPK GTRDYSPRQM AVREKVFDVI IRCFKRHGAE VIDTPV
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> Translation >> tRNA synthetase
Immunology >> Immune System Diseases >> Autoimmune
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Western blot - HARS antibody (ab55233)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55233 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. HARS is from the class II family of aminoacyl-tRNA synthetases. It is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.
Cellular localization
Cytoplasmic
Alternative names
- EC 6.1.1.21 antibody
- FLJ20491 antibody
- HisRS antibody
see all
Database links
- Entrez Gene: 3035 Human
- Omim: 142810 Human
- SwissProt: P12081 Human
- Unigene: 528050 Human
Anti-HARS antibody images:
Western blot - HARS antibody (ab55233)
HARS antibody (ab55233) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-HARS antibody (ab55233)
ab55233 has not yet been referenced specifically in any publications.
Publishing research using ab55233? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"