![Western blot - HAX1 antibody [9G3D11] (ab79723) image](#HAX1-Primary-antibodies-ab79723-1.jpg)
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Products:Cell Biology >> Apoptosis >> Mitochondrial
Overview
Product name
Anti-HAX1 antibody [9G3D11]
See all HAX1 products (4) ...
Description
Mouse monoclonal [9G3D11] to HAX1
Specificity
ab79723 is expected to recognize the longest isoform (HAX1a) as well as the shortest.
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Rat, Human
Immunogen
Synthetic peptide corresponding to 15 amino acids near the amino terminus of human HAX1.
Positive control
Human brain tissue lysate.
Properties
Form
Liquid
Storage instructions
Store at +4°C.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Clonality
Monoclonal
Clone number
9G3D11
Isotype
IgG1
Research areas
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Cell Biology >> Apoptosis >> Mitochondrial
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Western blot - HAX1 antibody [9G3D11] (ab79723)
![Western blot - HAX1 antibody [9G3D11] (ab79723) image](/ps/datasheet/images/79/ab79723/HAX1-Primary-antibodies-ab79723-1.jpg)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab79723 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: Use at an assay dependent dilution.
WB: Use a concentration of 1 - 2 µg/ml.Predicted molecular weight: 32 kDa.
Target
Relevance
HAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.
Cellular localization
Endoplasmic reticulum, Mitochondrial and Nuclear membrane. Note: Predominantly mitochondrial, but also to a lesser extent in endoplasmic reticulum and nuclear envelope.
Alternative names
- FLJ17042 antibody
- FLJ18492 antibody
- FLJ93803 antibody
see all
Database links
- Entrez Gene: 10456 Human
- Entrez Gene: 291202 Rat
- Omim: 605998 Human
- SwissProt: O00165 Human
- SwissProt: Q7TSE9 Rat
- Unigene: 199625 Human
Anti-HAX1 antibody [9G3D11] images:
Western blot - HAX1 antibody [9G3D11] (ab79723)
Lane 1 : Anti-HAX1 antibody [9G3D11] (ab79723) at 1 µg/ml
Lane 2 : Anti-HAX1 antibody [9G3D11] (ab79723) at 2 µg/ml
Lane 1 : Human brain tissue lysate
Lane 2 : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size : 32 kDa
Observed band size : 36 kDa (why is the actual band size different from the predicted?)
References for Anti-HAX1 antibody [9G3D11] (ab79723)
ab79723 has not yet been referenced specifically in any publications.
Publishing research using ab79723? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"