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Read our guarantee »Products:Cell Biology >> Apoptosis >> Mitochondrial
Anti-HAX1 antibody
See all HAX1 products (4) ...
Goat polyclonal to HAX1
ab81973 is expected to recognize both reported isoforms (NP_006109.2 and NP_001018238.1).
WB, ELISAmore details
Reacts with
Human
Synthetic peptide: C-TRHEADSSPRGDPES, corresponding to internal sequence amino acids 241-255 of human HAX1 according to NP_006109.2 (or 193-207 of NP_001018238.1).
C-TRHEADSS PRGDPES
Human kidney, liver and testis lysates.
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3
Concentration information loading...
Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Polyclonal
IgG
Epigenetics and Nuclear Signaling >> DNA / RNA >> RNA Processing >> Other
Cell Biology >> Apoptosis >> Mitochondrial
Western blot - HAX1 antibody (ab81973)
(enlarge)
Our Abpromise guarantee covers the use of ab81973 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Peptide ELISA: antibody detection limit dilution 1:2,000.
WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 32 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
HAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.
Endoplasmic reticulum, Mitochondrial and Nuclear membrane. Note: Predominantly mitochondrial, but also to a lesser extent in endoplasmic reticulum and nuclear envelope.
Western blot - HAX1 antibody (ab81973)

Anti-HAX1 antibody (ab81973) at 1 µg/ml + human testis lysate in RIPA buffer at 35 µg
developed using the ECL technique
Predicted band size : 32 kDa
Observed band size : 32 kDa
Exposure time : 1 hour
ab81973 has not yet been referenced specifically in any publications.
Publishing research using ab81973? Please let us know so that we can cite the reference in this datasheet
Concentration of lot no. is
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