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Western blot - HBXIP antibody (ab66258)
Western blot - HBXIP antibody (ab66258)
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Product Name 

HBXIP antibody

 

See all HBXIP antibodies (2)...

Product type 

Primary antibodies

Description 

Mouse polyclonal to HBXIP

Immunogen 

Recombinant full length protein (Human) with tag.

Reacts with 
(species key)

Hu

Tested applications 
(see key)

ELISA, WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: 1/1000 - 1/2500. Predicted molecular weight: 10 kDa.

This antibody has only been tested in WB against the recombinant protein used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Full length recombinant HBXIP with tag.

Cellular localization 

Cytoplasm.

Research areas 

Immunology >> Immune System Diseases >> Antiviral Signaling
Cell Biology >> Apoptosis >> Intracellular >> Caspases etc >> Inhibitors

Relevance 

HBXIP (Hepatitis B virus X interacting protein) complexes with the C-terminus of hepatitis B virus X protein (HBx) and down-regulates hepatitis B virus (HBV) replication. When complexed to BIRC5, it interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway.

 

Alternative names HBXIP antibody (ab66258)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

10542    (Human)

Omim

    

608521    (Human)

SwissProt

    

O43504    (Human)

Unigene

    

439815    (Human)

Raised in 

Mouse

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Whole antiserum

Storage buffer 

Preservative: None
Constituents: 50% Glycerol, Whole serum

Material safety datasheet (MSDS) for this product:
Glycerol MSDS

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this HBXIP antibody is on this datasheet. But please do contact us if you would like any reassurance!


See below for HBXIP antibody images, references, products related to ab66258 and other tools.

 

HBXIP antibody images:

Product image  Western blot - HBXIP antibody (ab66258)

Western blot - HBXIP antibody (ab66258)



Predicted band size : 10 kDa


Western blot against tagged recombinant protein immunogen using ab66258 HBXIP antibody at 1/1000 dilution. Predicted band size of immunogen is 36 kDa.

 
 

Search PubMed (MEDLINE) for references to HBXIP

 

HBXIP antibody - more information

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