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Anti-HDAC10 antibody [EPR3576] (ab108934)

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Overview

Product name

Anti-HDAC10 antibody [EPR3576]
See all HDAC10 products (7) ...

Description

Rabbit monoclonal [EPR3576] to HDAC10

Tested applications

WB, IP, ICCmore details

Cross reactivity

Reacts with

Mouse, Human

Does not react with

Rat

Immunogen

A synthetic peptide corresponding to residues in Human HDAC10

Positive control

HeLa, 293T, Jurkat, HepG2, A673 and NIH/3T3 cell lysates

General notes

Produced under U.S. Patent No. 5,675,063.

Properties

Form

Liquid

Storage instructions

Store at -20°C. Stable for 12 months at -20°C

Storage buffer

PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

EPR3576

Isotype

IgG1

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HDACs >> Class I
Stem Cells >> Signaling Pathways >> Wnt >> HDACs
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation

  • Western blot - HDAC10 antibody [EPR3576] (ab108934)Western blot - HDAC10 antibody [EPR3576] (ab108934) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab108934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/1000 - 1/10000. Pr...Read more →

    WB: 1/1000 - 1/10000. Predicted molecular weight: 75 kDa.

  • IP

     IP: 1/10 - 1/100.

    IP: 1/10 - 1/100.

  • ICC

     ICC: 1/100 - 1/250.

    ICC: 1/100 - 1/250.

Application notes

Is unsuitable for ,Flow Cyt or IHC-P.

Target

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Tissue specificity

Ubiquitous. High expression in liver, spleen, pancreas and kidney.

Sequence similarities

Belongs to the histone deacetylase family. HD type 2 subfamily.

Cellular localization

Cytoplasm. Nucleus. Excluded from the nucleoli.

Target information above from: UniProt accessionQ969S8 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • DKFZP761B039 antibody
  • HD 10 antibody
  • HD10 antibody
  • HDA10_HUMAN antibody
  • HDAC 10 antibody
  • Hdac10 antibody
  • Histone deacetylase 10 antibody
  • MGC149722 antibody
  • OTTHUMP00000028555 antibody
see all

Database links

Anti-HDAC10 antibody [EPR3576] images:

  Western blot - HDAC10 antibody [EPR3576] (ab108934)

Western blot - HDAC10 antibody [EPR3576] (ab108934)

All lanes : Anti-HDAC10 antibody [EPR3576] (ab108934) at 1/1000 dilution

Lane 1 : HeLa cell lysate
Lane 2 : 293T cell lysate
Lane 3 : Jurkat cell lysate
Lane 4 : HepG2 cell lysate
Lane 5 : A673 cell lysate
Lane 6 : NIH/3T3 cell lysate

Lysates/proteins at 10 µg per lane.


Predicted band size : 75 kDa

References for Anti-HDAC10 antibody [EPR3576] (ab108934)

ab108934 has not yet been referenced specifically in any publications.

Publishing research using ab108934? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"