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Anti-HDAC11 antibody (ab98041)

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Overview

Product name

Anti-HDAC11 antibody
See all HDAC11 products (4) ...

Description

Rabbit polyclonal to HDAC11

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat

Immunogen

Synthetic peptide corresponding to a region within internal sequence amino acids 143-192 (HCSSDRGGGF CAYADITLAI KFLFERVEGI SRATIIDLDA HQGNGHERDF) of Human HDAC11 (NP_079103).

HCSSDRGGGFCAYADITLAIKFLFERVEGISRATIIDLDA HQGNGHERDF

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Positive control

Human Fetal Small Intestine Lysate

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 2% Sucrose, PBS

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HDACs >> Class I
Stem Cells >> Signaling Pathways >> Wnt >> HDACs
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation

  • Western blot - HDAC11 antibody (ab98041)Western blot - HDAC11 antibody (ab98041) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab98041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

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    WB

     WB: Use a concentration ...Read more →

    WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 39 kDa.Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

Function

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.

Tissue specificity

Weakly expressed in most tissues. Strongly expressed in brain, heart, skeletal muscle, kidney and testis.

Sequence similarities

Belongs to the histone deacetylase family.

Cellular localization

Nucleus. Predominantly nuclear.

Target information above from: UniProt accessionQ96DB2 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • FLJ22237 antibody
  • HD 11 antibody
  • HD11 antibody
  • HDA11_HUMAN antibody
  • HDAC 11 antibody
  • HDAC11 antibody
  • Histone deacetylase 11 antibody
see all

Database links

see all

Anti-HDAC11 antibody images:

  Western blot - HDAC11 antibody (ab98041)

Western blot - HDAC11 antibody (ab98041)

Anti-HDAC11 antibody (ab98041) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human Fetal Small intestine Lysate at 10 µg

Secondary
HRP conjugated anti-Rabbit IgG at 1/50000 dilution

Predicted band size : 39 kDa


Gel concentration: 12%

References for Anti-HDAC11 antibody (ab98041)

ab98041 has not yet been referenced specifically in any publications.

Publishing research using ab98041? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"