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Overview

  • Product nameHDAC6 peptideSee all HDAC6 proteins and peptides ...
  • Protein descriptionThis peptide was used as an immunogen for ab1440 - HDAC6 antibody.

    • Properties

  • Purification notesThe peptide ab41708 is a crude desalted synthetic peptide, purity range from 60-80%.
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab41708 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Blocking
    WB
  • Application notesBL: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 131 kDa.

    The peptide is used for blocking the antibody activity of HDAC6. It usually blocks the antibody activity completely in Western blot analysis by incubating the peptide with equal volume of antibody for 30 minutes at 37degC.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        FLJ16239HD 6HD6
        HD6HDAC 6HDAC6HDAC6_HUMANHistone deacetylase 6Histone deacetylase 6 (HD6)Histone deacetylase 6 (HD6).Histone deacetylase 6 (HD6).JM 21JM21JM21KIAA0901KIAA0901OTTHUMP00000032398OTTHUMP00000197663
      see all
  • FunctionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
  • Sequence similaritiesBelongs to the histone deacetylase family. HD type 2 subfamily.
    Contains 1 UBP-type zinc finger.
  • Post-translational
    modifications    Ubiquitinated. Its polyubiquitination however does not lead to its degradation.
    Sumoylated in vitro.
  • Cellular localizationNucleus. Cytoplasm. It is mainly cytoplasmic, where it is associated with microtubules.

    • Target information above from: UniProt accession Q9UBN7 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for HDAC6 peptide (ab41708)

    ab41708 has not yet been referenced specifically in any publications.

    Publishing research using ab41708 ? Please let us know so that we can cite the reference in this datasheet

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"