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Western blot - HDAC8 antibody (ab23658)

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Product Name
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HDAC8 antibody
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See all HDAC8 antibodies (5)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to HDAC8
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Immunogen
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Synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Human HDAC8. (Peptide available as ab27458.)
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Reacts with
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Hu
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Predicted to react
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Ms (Due to sequence homology)
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Tested applications
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 41 kDa (predicted molecular weight: 41 kDa).
Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nucleus. Excluded from the nucleoli.
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Research areas
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Cardiovascular >> Heart >> Hypertrophy >> Other Chromatin and Nuclear Signaling >> Chromatin Modifying Enzymes >> Acetylation >> HDACs >> Class I Stem Cells >> Signaling Pathways >> Wnt >> HDACs Chromatin and Nuclear Signaling >> Transcription >> Other factors
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Relevance
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter.
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Database links
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The links below go to external sites and will open in a new browser window
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide Constituents: 1% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product: Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this HDAC8 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for HDAC8 antibody images, references, products related to ab23658 and other tools.
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HDAC8 antibody images:
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Search PubMed (MEDLINE) for references to HDAC8
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HDAC8 antibody - more information
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Customer reviews (feedback) regarding HDAC8 antibody |
Customer FAQs regarding HDAC8 antibody |
Protocols for HDAC8 antibody |
Price and availability of products related to HDAC8 antibody |
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HDAC8 antibody - related products:
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HDAC8 antibody - other tools:
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Contact Abcam with a Technical Enquiry about HDAC8 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"