Overview

  • Product nameAnti-HDL antibody [1C5]
    See all HDL primary antibodies
  • Description
    Mouse monoclonal [1C5] to HDL
  • SpecificityThe antibody reacts with high density lipoproteins (HDL 2, HDL 3, apo A1) of plasma. No crossreactions with other plasma proteins were detected.
  • Tested applicationsELISA, IHC-Fr, more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native human serum protein (purified) containing human HDL 2, HDL 3, and APO-A1 lipoproteins.

  • General notes


    This antibody increases the specific binding of HDL to rat and human hepatocytes and the efflux of cholesterol from hepatocytes prelabelled with 14C acetate.

Properties

Applications

Our Abpromise guarantee covers the use of ab34788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
IHC-Fr 1/100.
Depletion Use at an assay dependent concentration.

Use in a solid phase system.

Target

  • Relevance

    High-density lipoprotein (HDL) is one of the five major groups of lipoproteins, which, in order of sizes, largest to smallest, are chylomicrons, VLDL, IDL, LDL, and HDL, which enable lipids like cholesterol and triglycerides to be transported within the water-based bloodstream. In healthy individuals, about thirty percent of blood cholesterol is carried by HDL.

    Blood tests typically report HDL-C level, i.e. the amount of cholesterol contained in HDL particles. It is often contrasted with low-density or LDL cholesterol or LDL-C. HDL particles are able to remove cholesterol from within artery atheroma and transport it back to the liver for excretion or re-utilization, which is the main reason why the cholesterol carried within HDL particles (HDL-C) is sometimes called "good cholesterol" (despite the fact that it is exactly the same as the cholesterol in LDL particles).

  • Alternative names
    • High Density Lipoprotein antibody

References for Anti-HDL antibody [1C5] (ab34788)

This product has been referenced in:
  • Lu J  et al. Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis. Proc Natl Acad Sci U S A 111:5189-94 (2014). Read more (PubMed: 24706838) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"