Overview
- Product nameAnti-HDL antibody [1C5]See all HDL primary antibodies ...
- DescriptionMouse monoclonal [1C5] to HDL
- SpecificityThe antibody reacts with high density lipoproteins (HDL 2, HDL 3, apo A1) of plasma. No crossreactions with other plasma proteins were detected.
- Tested applicationsELISA, IHC-Fr, more details
- Species reactivityReacts with: Human
- Immunogen
Full length native human serum protein (purified) containing human HDL 2, HDL 3, and APO-A1 lipoproteins.
Properties
- FormLiquid
- Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
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Concentration information loading... - Purification notesThis antibody was purified by sodium sulfate and DEAE cellulose chromatography.
- Primary antibody notes This antibody increases the specific binding of HDL to rat and human hepatocytes and the efflux of cholesterol from hepatocytes prelabelled with 14C acetate.
- Clonality Monoclonal
- Clone number1C5
- IsotypeIgG1
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab34788 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| ELISA | |
| IHC-Fr | |
| Depletion |
ELISA: 1/1000.
IHC-Fr: 1/100.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- Relevance
High-density lipoprotein (HDL) is one of the five major groups of lipoproteins, which, in order of sizes, largest to smallest, are chylomicrons, VLDL, IDL, LDL, and HDL, which enable lipids like cholesterol and triglycerides to be transported within the water-based bloodstream. In healthy individuals, about thirty percent of blood cholesterol is carried by HDL.
Blood tests typically report HDL-C level, i.e. the amount of cholesterol contained in HDL particles. It is often contrasted with low-density or LDL cholesterol or LDL-C. HDL particles are able to remove cholesterol from within artery atheroma and transport it back to the liver for excretion or re-utilization, which is the main reason why the cholesterol carried within HDL particles (HDL-C) is sometimes called "good cholesterol" (despite the fact that it is exactly the same as the cholesterol in LDL particles).
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Alternative names
- High Density Lipoprotein antibody
References for Anti-HDL antibody [1C5] (ab34788)
ab34788 has not yet been referenced specifically in any publications.
