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Western blot - HEY1 antibody (ab57121)
(enlarge)
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Product Name
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HEY1 antibody
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See all HEY1 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to HEY1
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Immunogen
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Recombinant fragment: DYRSLGFREC LAEVARYLSI IEGLDASDPL RVRLVSHLNN YASQREAASG AHAGLGHIPW GTVFGHHPHI AHPLLLPQNG HGNAGTTASP TEPHHQGRLG , corresponding to amino acids 121-221 of Human HEY1
BLAST 'DYRSLGFREC LAEVARYLSI IEGLDASDPL RVRLVSHLNN YASQREAASG AHAGLGHIPW GTVFGHHPHI AHPLLLPQNG HGNAGTTASP TEPHHQGRLG ' with  or 
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear
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Research areas
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Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Co-activators/co-repressors
Chromatin and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH
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Relevance
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Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. HEY genes are direct transcriptional targets of the Notch signaling pathways in Drosophila and vertebrates. Hey1 functions as a corepressor, providing a mechanism of cross-talk between Notch and androgen signaling pathways. It is excluded from the nucleus in most human prostate cancers.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this HEY1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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HEY1 antibody images:
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 Western blot - HEY1 antibody (ab57121)
Western blot against tagged recombinant protein immunogen using ab57121 HEY1 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa
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Search PubMed (MEDLINE) for references to HEY1
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HEY1 antibody - more information
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Customer reviews (feedback) regarding HEY1 antibody |
Customer FAQs regarding HEY1 antibody |
Protocols for HEY1 antibody |
Price and availability of products related to HEY1 antibody |
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HEY1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about HEY1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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