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Anti-HEY2 antibody (ab86010)

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Overview

Product name

Anti-HEY2 antibody
See all HEY2 products (4) ...

Description

Rabbit polyclonal to HEY2

Tested applications

WBmore details

Cross reactivity

Reacts with

Mouse, Human

Immunogen

3 synthetic peptides (Human) conjugated to KLH

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.01% Thimerosal (merthiolate)
Constituents: Whole serum

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Cardiovascular >> Heart >> Cardiogenesis >> Transcription factors/regulators
Stem Cells >> Signaling Pathways >> Notch >> Nuclear
Epigenetics and Nuclear Signaling >> Transcription >> Domain Families >> HLH / Leucine Zipper >> HLH

  • Western blot - HEY2 antibody (ab86010)Western blot - HEY2 antibody (ab86010) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab86010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/1000Detects a band...Read more →

    WB: 1/1000Detects a band of approximately 50 kDa (predicted molecular weight: 50 kDa).

Target

Function

Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

Sequence similarities

Belongs to the HEY family.
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 Orange domain.

Cellular localization

Nucleus.

Target information above from: UniProt accessionQ9UBP5 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • bHLHb32 antibody
  • Cardiovascular helix loop helix factor 1 antibody
  • Cardiovascular helix-loop-helix factor 1 antibody
  • CHF1 antibody
  • Class B basic helix-loop-helix protein 32 antibody
  • GRIDLOCK antibody
  • GRL antibody
  • Hairy and enhancer of split related 2 antibody
  • Hairy and enhancer of split-related protein 2 antibody
  • Hairy related transcription factor 2 antibody
  • Hairy-related transcription factor 2 antibody
  • Hairy/enhancer-of-split related with YRPW motif protein 2 antibody
  • hCHF1 antibody
  • HERP antibody
  • HERP1 antibody
  • HES related repressor protein 1 antibody
  • HES-related repressor protein 2 antibody
  • HESR-2 antibody
  • HESR2 antibody
  • HEY2 antibody
  • HEY2_HUMAN antibody
  • hHRT2 antibody
  • HRT-2 antibody
  • HRT2 antibody
  • Protein gridlock homolog antibody
see all

Database links

Anti-HEY2 antibody images:

  Western blot - HEY2 antibody (ab86010)

Western blot - HEY2 antibody (ab86010)

All lanes : Anti-HEY2 antibody (ab86010) at 1/1000 dilution

Lane 1 : Uninduced culture
Lane 2 : Induced culture of E.coli

Secondary
anti-Rabbit IgG HRP at 1/1000 dilution

Predicted band size : 50 kDa

References for Anti-HEY2 antibody (ab86010)

ab86010 has not yet been referenced specifically in any publications.

Publishing research using ab86010? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"