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Products:Neuroscience >> Neurology process >> Neurogenesis
Overview
Product name
HGFA Inhibitor 2 peptide (Between KD1 and KD2)
See all HGFA Inhibitor 2 products (2) ...
Protein description
Synthetic peptide HGFA Inhibitor 2. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab28334 - HGFA Inhibitor 2 antibody - Between KD1 and KD2.
Properties
Purity
>95% by SDS-PAGE
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 0.001% Tween 20, 30mM HEPES, 2mM EDTA, 150mM Sodium chloride, pH 6.75
Concentration
Concentration information loading...
Applications
Show applications key
Our Abpromise guarantee covers the use of ab41272 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB
ELISA
Application notes
ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This peptide can be used with studies using ab28334. Dilution optimised using Chromogenic detection. Not yet tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Protein info
Function
Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.
Tissue specificity
Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.
Involvement in disease
Defects in SPINT2 are the cause of diarrhea type 3 (DIAR3) [MIM:270420]; also known as congenital sodium diarrhea (CSD). DIAR3 is a rare, inherited diarrhea of infancy. A diagnosis of DIAR3 is made on the findings of a life-threatening secretory diarrhea, severe metabolic acidosis, and hyponatremia secondary to extraordinarily high fecal losses of sodium, with low or normal excretion of urinary sodium, in the absence of infectious, autoimmune, and endocrine causes.
Sequence similarities
Contains 2 BPTI/Kunitz inhibitor domains.
Domain
This inhibitor contains two inhibitory domains.
Cellular localization
Membrane.
Target information above from: UniProt accessionO43291
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for HGFA Inhibitor 2 peptide (Between KD1 and KD2) (ab41272)
ab41272 has not yet been referenced specifically in any publications.
Publishing research using ab41272? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"