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Products:Cardiovascular >> Hypoxia >> HIF

Anti-HIF1 alpha antibody [H1alpha67] - ChIP Grade (ab1)

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Publishing research using ab1? Please let us know so that we can cite the reference in this datasheet

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ab1 has been referenced in 35 publications.

  1. Bensellam M et al. Glucose-induced O2 consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells. PLoS One 7:e29807 (2012). WB. PubMed: 22235342
  2. Paatero I et al. Interaction with ErbB4 promotes hypoxia-inducible factor-1a signaling. J Biol Chem : (2012). IHC-P; Mouse. PubMed: 22308027
  3. Ingraham CA et al. Matrix Metalloproteinase (MMP)-9 Induced by Wnt Signaling Increases the Proliferation and Migration of Embryonic Neural Stem Cells at Low O2 Levels. J Biol Chem 286:17649-57 (2011). WB; Rat. PubMed: 21460212
  4. Bento CF et al. Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction. Exp Physiol 95:955-70 (2010). WB, IHC-Fr; Human, Rat. PubMed: 20562294
  5. Pereira ER et al. Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response. PLoS One 5: (2010). WB; Rat. PubMed: 20824063
  6. Itoigawa Y et al. Hypoxia induces adipogenic differentitation of myoblastic cell lines. Biochem Biophys Res Commun 399:721-6 (2010). WB; Mouse. PubMed: 20692234
  7. Fisher CD et al. Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease. Drug Metab Dispos 37:2087-94 (2009). PubMed: 19651758
  8. Bailey JM et al. Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer. Oncogene 28:3513-25 (2009). WB. PubMed: 19633682
  9. Chiacchiera F et al. p38alpha blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1alpha- to FoxO-dependent transcription. Cell Death Differ 16:1203-14 (2009). WB; Human. PubMed: 19343039
  10. Walczak-Drzewiecka A et al. HIF-1alpha is up-regulated in activated mast cells by a process that involves calcineurin and NFAT. J Immunol 181:1665-72 (2008). WB; Human. PubMed: 18641302
  11. Kane R et al. Chordin-like 1, a bone morphogenetic protein-4 antagonist, is upregulated by hypoxia in human retinal pericytes and plays a role in regulating angiogenesis. Mol Vis 14:1138-48 (2008). WB; Human. PubMed: 18587495
  12. Natarajan R et al. Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium. Am J Physiol Heart Circ Physiol 293:H1571-80 (2007). PubMed: 17545479
  13. Natarajan R et al. Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury. Circ Res 98:133-40 (2006). PubMed: 16306444
  14. Critchley HO et al. Hypoxia-inducible factor-1alpha expression in human endometrium and its regulation by prostaglandin E-series prostanoid receptor 2 (EP2). Endocrinology 147:744-53 (2006). PubMed: 16282352
  15. Pisani DF et al. SMHS1 is involved in oxidative/glycolytic-energy metabolism balance of muscle fibers. Biochem Biophys Res Commun 326:788-93 (2005). PubMed: 15607738
  16. Bos R et al. Hypoxia-inducible factor-1alpha is associated with angiogenesis, and expression of bFGF, PDGF-BB, and EGFR in invasive breast cancer. Histopathology 46:31-6 (2005). PubMed: 15656883
  17. Berger AP et al. Increased growth factor production in a human prostatic stromal cell culture model caused by hypoxia. Prostate 57:57-65 (2003). PubMed: 12886524
  18. Coradini D et al. Infiltrating ductal and lobular breast carcinomas are characterised by different interrelationships among markers related to angiogenesis and hormone dependence. Br J Cancer 87:1105-11 (2002). PubMed: 12402149
  19. Haugland HK et al. Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation. Int J Radiat Oncol Biol Phys 53:854-61 (2002). PubMed: 12095550
  20. Gardner LB et al. Hypoxia inhibits G1/S transition through regulation of p27 expression. J Biol Chem 276:7919-26 (2001). PubMed: 11112789
  21. Yu F et al. Dynamic, site-specific interaction of hypoxia-inducible factor-1alpha with the von Hippel-Lindau tumor suppressor protein. Cancer Res 61:4136-42 (2001). PubMed: 11358837
  22. Schindl M et al. DNA repair-redox enzyme apurinic endonuclease in cervical cancer: evaluation of redox control of HIF-1alpha and prognostic significance. Int J Oncol 19:799-802 (2001). PubMed: 11562758
  23. Duyndam MC et al. Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite. J Biol Chem 276:48066-76 (2001). PubMed: 11641398
  24. Itoh T et al. Reversible inhibition of hypoxia-inducible factor 1 activation by exposure of hypoxic cells to the volatile anesthetic halothane. FEBS Lett 509:225-9 (2001). PubMed: 11741593
  25. Volm M & Koomägi R Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer. Anticancer Res 20:1527-33 (2000). PubMed: 10928066
  26. Palmer LA et al. Normoxic stabilization of hypoxia-inducible factor-1 expression and activity: redox-dependent effect of nitrogen oxides. Mol Pharmacol 58:1197-203 (2000). PubMed: 11093754
  27. Ravi R et al. Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha. Genes Dev 14:34-44 (2000). PubMed: 10640274
  28. Zhong H et al. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics. Cancer Res 60:1541-5 (2000). PubMed: 10749120
  29. Rivard A et al. Age-dependent defect in vascular endothelial growth factor expression is associated with reduced hypoxia-inducible factor 1 activity. J Biol Chem 275:29643-7 (2000). PubMed: 10882714
  30. Chandel NS et al. Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing. J Biol Chem 275:25130-8 (2000). PubMed: 10833514
  31. Agani FH et al. The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia. J Biol Chem 275:35863-7 (2000). PubMed: 10961998
  32. Birner P et al. Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer. Cancer Res 60:4693-6 (2000). PubMed: 10987269
  33. Feldser D et al. Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2. Cancer Res 59:3915-8 (1999). PubMed: 10463582
  34. Nguyen SV & Claycomb WC Hypoxia regulates the expression of the adrenomedullin and HIF-1 genes in cultured HL-1 cardiomyocytes. Biochem Biophys Res Commun 265:382-6 (1999). PubMed: 10558876
  35. Zhong H et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res 59:5830-5 (1999). PubMed: 10582706

Publishing research using ab1? Please let us know so that we can cite the reference in this datasheet

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