Anti-HIF1AN antibody (ab57601)

Overview

• Product nameAnti-HIF1AN antibodySee all HIF1AN primary antibodies ...
• Description
  Mouse monoclonal to HIF1AN
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Recombinant full length protein, corresponding to amino acids 1-350 of Human HIF1AN

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  PBS, pH 7.2
• Concentration information loading...
• PurityProtein G purified
• Clonality Monoclonal
• IsotypeIgG2a
• Light chain typekappa
• Research Areas
  • Cancer
  • Invasion/microenvironment
  • Hypoxia
  • HIF

  • Cancer
  • Invasion/microenvironment
  • Hypoxia
  • Hydroxylases

  • Epigenetics and Nuclear Signaling
  • Chromatin Modifying Enzymes
  • Methylation

  • Epigenetics and Nuclear Signaling
  • Chromatin Modifying Enzymes
  • Jumonji containing proteins

  • Epigenetics and Nuclear Signaling
  • Cardiovascular/Immune
  • Hypoxia
  • HIF

Applications

Target

• FunctionHydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
• Sequence similaritiesContains 1 JmjC domain.
• Cellular localizationNucleus.

Target information above from: UniProt accession Q9NWT6 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Clone ID: BC007719 Human
  • Entrez Gene: 55662 Human
  • IMAGE Id: 4138066 Human
  • Omim: 606615 Human
  • SwissProt: Q5W147 Human
  • SwissProt: Q9NWT6 Human
  • Unigene: 500788 Human

• Alternative names
  DKFZp762F1811 antibodyFactor inhibiting HIF-1 antibodyFactor inhibiting HIF1 antibody

  FIH 1 antibodyFIH-1 antibodyFIH1 antibodyFLJ20615 antibodyFLJ22027 antibodyHIF1AN antibodyHIF1N_HUMAN antibodyHypoxia inducible factor 1 alpha inhibitor antibodyHypoxia inducible factor 1 alpha subunit inhibitor antibodyHypoxia inducible factor asparagine hydroxylase antibodyHypoxia-inducible factor 1-alpha inhibitor antibodyHypoxia-inducible factor asparagine hydroxylase antibodyPeptide aspartate beta dioxygenase antibody

  see all

Anti-HIF1AN antibody images

• 

  Western blot - HIF1AN antibody (ab57601)
  
  
  Predicted band size : 40 kDa
  HIF1AN antibody (ab57601) at 1ug/lane + Jurkat cell lysate at 25ug/lane.