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Overview

  • Product nameHIF1AN peptideSee all HIF1AN proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 250 to the C-terminus of Human FIH/asparagine hydroxylase.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab12289 - FIH/asparagine hydroxylase antibody.
  • Protein length349 amino acids

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab12289.

    • Protein info

    • Alternative names
        DKFZp762F1811Factor inhibiting HIF 1Factor inhibiting HIF-1
        Factor inhibiting HIF1FIH 1FIH-1FIH1FLJ20615FLJ22027HIF1ANHIF1N_HUMANHypoxia inducible factor 1 alpha inhibitorHypoxia inducible factor 1 alpha subunit inhibitorHypoxia inducible factor asparagine hydroxylaseHypoxia-inducible factor 1-alpha inhibitorHypoxia-inducible factor asparagine hydroxylasePeptide aspartate beta dioxygenaseprolyl hydroxylase
      see all
  • FunctionHydroxylates HIF-1 alpha at 'Asp-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases.
  • Sequence similaritiesContains 1 JmjC domain.
  • Cellular localizationNucleus.

    • Target information above from: UniProt accession Q9NWT6 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for HIF1AN peptide (ab12306)

    ab12306 has not yet been referenced specifically in any publications.

    Publishing research using ab12306 ? Please let us know so that we can cite the reference in this datasheet

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