Overview
Product nameHIV1 gp120 + gp41 + HIV2 gp 39 protein
Protein descriptionRecombinant fusion protein containing the C terminus of gp120 and most of gp41. The protein is conjugated to a 23 amino acid synthetic peptide derived from gp39 of HIV-2. 27 kDa.
Expression hostE. coli
Properties
Purity> 95
% by SDS-PAGE
Purification notesPurity is greater than 95.0% as determined by HPLC analysis and SDS-PAGE.
Biological activityab68872 is immunoreactive with all sera of HIV1, HIV type O & HIV2 infected individuals.
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 6.00
Constituents: 0.05% SDS, 1.64% Sodium phosphate
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab68872
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| WB |
WB: Use at an assay dependent dilution. |
| ELISA |
ELISA: Use at an assay dependent dilution. |
Protein info
-
Alternative names
Glycoprotein 120Glycoprotein 41HIV1 gp120
see all
Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
References for HIV1 gp120 + gp41 + HIV2 gp 39 protein (ab68872)
ab68872
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
