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HIV1 gp120 + gp41 protein (ab68127)

Submit an Abreview Q&A (2)

Overview

  • Product nameHIV1 gp120 + gp41 proteinSee all HIV1 gp120 + gp41 proteins and peptides ...
  • Protein descriptionE.coli-derived recombinant fusion protein that composes all of the reported immunogenic determinants found in HIV1 gp41 and a small portion of gp120. HIV1 gp120 + gp41 spans the C-Terminus of gp120 and most of gp41.
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Biological activityab68127 is immunoreactive with all sera of HIV1 and HIV-type O infected individuals and with 60-80% of HIV2 infected individuals.
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 0.5X PBS, 6M Urea
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab68127 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent dilution. Predicted molecular weight: 28 kDa.
    ELISA ELISA: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        Glycoprotein 120Glycoprotein 41HIV1 gp120
        HIV1 gp41SUTM
      see all
  • Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.

    • References for HIV1 gp120 + gp41 protein (ab68127)

    ab68127 has not yet been referenced specifically in any publications.

    Publishing research using ab68127 ? Please let us know so that we can cite the reference in this datasheet

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    Submit an Abreview for ab68127 Submit a Question for ab68127

    Displaying 1 - 2 of 2 results for Abreviews and Q&A

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    Votes: Highest First

    1. I would like to know the HIV subtype on which the following proteins are based: ab68127, ab68872, 43024.



    ab68127 corresponds to Strain MN



    I am still awaiting strain information regarding ab68872. I will forward this to you as soon as it is available.

    Hello,

    We would like to immobilize Anti-HIV1 gp120 onto a surface to show efficacy in capturing HIV protein.

    Our current thought is to:
    1. Immobilize Anti-HIV1 gp120 antibody (Product # ab21179)
    2.Capture HIV1 gp120 + gp41 pro...

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    Thank you for contacting us. Theoretically your outline makes sense. However, we have not tested the products this way and cannot guarantee that the binding sites of the antibodies will not interfere with each other. I hope this is helpful. Please le me k...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"