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Overview

  • Product nameHIV1 gp120 proteinSee all HIV1 gp120 proteins and peptides ...
  • Protein descriptionRecombinant fragment, corresponding to amino acids 30-110 of the N-terminus immunodominant regions of HIV1 gp120
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesPurity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
  • Biological activityab73769 is immunoreactive with all sera of HIV1 infected individuals.
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 8M Urea, 100mM Sodium phosphate, 10mM Tris HCl, pH 4.5
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab73769 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB
    ELISA
  • Application notesELISA: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution.

    Note: ab73769is an excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Protein info

    • Alternative names
        Glycoprotein 120gp120SUSurface protein
  • RelevanceHIV1 is equipped with the envelope gp160 glycoprotein for interaction with Langerhans cells (LCs) and dendritic cells (DCs), the members of the innate immune system, which confront the virus at the portal of virus entry in the human body. These cells are equipped with receptors by which they bind and endocytose the virus. The gp120 glycoprotein is used for binding to CD4 receptor and CCR5 co-receptor of T helper 2 (Th2) cells, and is able to induce FcepsilonRI(+) hematopoietic cells to produce IL4, which inactivates the host adaptive immune response.
  • Cellular localizationEnvelope surface glycoprotein.

    • References for HIV1 gp120 protein (ab73769)

    ab73769 has not yet been referenced specifically in any publications.

    Publishing research using ab73769 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab73769 Submit a Question for ab73769

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    Inquiry: I am just interested in further details/clarifications of product information. Your product datasheet says amino acids 30-110, but the link that you give for the answer to question 2 (http://www.uniprot.org/blast/?about=P04578[33-511]) says ...

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    Thank you for contacting us. The link does bring you to the sequence for the full protein and from there you can pull out the actual sequence of the protein fragment which is aa 3-110 as stated on the datasheet. I am not sure why it comes up highlighted i...

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    Testing discount code to try ab73769 in ELISPOT

    DISCOUNT CODE: *
    Expiration date: *

    I am very pleased to hear you would like to accept our offer and test ab73769 in ELISPOT. This code will give you: 1 free PROTEIN before the expiration date. To redeem this offer, please submit an Abreview ...

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    Hi, Can you give me the protein sequence of this product ab73769. (corresponding of the N-terminus immunodominat regions of HIV1 gp120) Thanks in advance,

    Thank you for contacting Abcam about ab73769. The protein sequence that you requested can be obtained by clicking on the link below. It can also be found by using the uniprot ID#P04578. http://www.uniprot.org/blast/?about=P04578[33-511] ...

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    will test ab73769 and ab69717 in Functional Studies

    Thank you for your phone call. DISCOUNT CODE: xxx for ab73769 DISCOUNT CODE: xxx for ab69717 Expiration date: xxx I am very pleased to hear you would like to accept our offer and test ab73769 and ab69717 in Functional Studies. E...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"