Overview
Product nameHIV1 gp41 protein (HRP)See all HIV1 gp41 proteins and peptides ...
Protein descriptionRecombinant full length HIV1 gp41 HRP labeled; contains the full-length sequence of HIV1 gp41 immunodominant regions.
Expression hostE. coli
ConjugationHRP
Properties
Purity> 95
% by SDS-PAGE
Purification notesPurity: Greater than 95.0% as determined by HPLC analysis and SDS-PAGE
Biological activityThis protein is immunoreactive with all sera of HIV-1 infected individuals.
FormLiquid
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: None
Constituents: 8M Urea, 20mM PBS, 20mM Sodium chloride, 1mM DTT, pH 7.8
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab68935
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| WB |
|
| ELISA |
|
Application notesELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
Note: ab68935 is useful for early detection of HIV seroconvertors with minimal specificity problems.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
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Alternative names
EnvEnvelope glycoprotein gp160Envelope Protein gp120
Glycoprotein 41gp41Human Immunodeficiency Virus 1Human Immunodeficiency Virus Type 1 gp41TMTransmembrane protein
see all
Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.
References for HIV1 gp41 protein (HRP) (ab68935)
ab68935
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
