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Overview

  • Product nameHIV1 gp41 protein (Tagged)See all HIV1 gp41 proteins and peptides ...
  • Protein descriptionRecombinant fragment of HIV1 env antigen, Amino acids 466-753 of the HIV1 env region, MW 32 kDa; fused to ß-galactosidase (114 kDa) at the N- terminus.
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Biological activityReacts strongly with human HIV positive serum.
  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 8M Urea, 20mM Tris HCl, 10mM Beta mercaptoethanol, pH 8
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab49068 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    ELISA ELISA: Use at an assay dependent dilution.
    WB WB: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        EnvEnv polyproteinEnvelope glycoprotein gp160
        Envelope Protein gp120Glycoprotein 41GP120gp41Human Immunodeficiency Virus 1Human Immunodeficiency Virus Type 1 gp41TMTransmembrane protein
      see all
  • Relevancegp41/120 is the major HIV protein associated with the HIV envelope. It functions as the viral antireceptor or attachment protein. gp41 (or TM) traverses the envelope, whereas gp120 is present on the outer surface and is noncovalently attached to gp41. The precursor of gp120/41 (gp160) is synthesized in the endoplasmic reticulum and is transported via the golgi body to the cell surface. Upon activation of the envelope glycoprotein (gp120/41) by cellular receptors, gp41 undergoes conformational changes that mediate fusion of the viral and cellular membranes.

    • References for HIV1 gp41 protein (Tagged) (ab49068)

    ab49068 has not yet been referenced specifically in any publications.

    Publishing research using ab49068 ? Please let us know so that we can cite the reference in this datasheet

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