Overview
Product nameHIV1 p17 + p24 protein (Tagged)
Protein descriptionThis recombinant protein contains the HIV-1 immunodominant regions from gag p17-p24, and is tagged at the N-terminus.
Expression hostE. coli
Properties
Purity> 95
% by SDS-PAGE
Biological activityReacts strongly with human HIV positive serum.
FormLiquid
Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: None
Constituents: 50% Glycerol, 0.2% Triton-X-100, 1.5M Urea, 25mM Tris HCl, pH 8
Concentration information loading...
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab49081
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|
Application
|
Notes |
| ELISA |
ELISA: Use at an assay dependent dilution. |
| WB |
WB: Use at an assay dependent dilution. |
Protein info
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Alternative names
CACapsid proteinCapsid protein p24
Human Immunodeficiency virus 1MAMatrix proteinMatrix protein p17
see all
RelevanceHIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors function during viral assembly to selectively bind and package two plus strands of genomic RNA. HIV1 p17 is the matrix protein of the Gag polyprotein.
Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.
Cellular localizationCell Membrane
References for HIV1 p17 + p24 protein (Tagged) (ab49081)
ab49081
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"