Recombinant HIV1 p24 protein (ab43037)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Suitable for: ELISA, WB
Description
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Product name
Recombinant HIV1 p24 protein
See all HIV1 p24 proteins and peptides -
Biological activity
Immunoreactive with all sera of HIV1 infected individuals. -
Purity
> 95 % SDS-PAGE.
Organic extraction > S-Sepharose > S-300. -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Sequence
PIVQN IQGQMVHQAI SPRTLNAWVK VVEEKAFSPE VIPMFSALSE GATPQDLNTM LNTVGGHQAA MQMLKETINE EAAEWDRLHP AHAGPIAPGQ MREPRGSDIA GTTSTLQEQI GWMTNNPPIP VGEIYKRWII LGLNKIVRMY SPSSILDIRQ GPKEPFRDYV DRFYKTLRAE QASQEVKNWM TETLLVQNAN PDCKTILKAL GPAATLEEMM TACQGVGGPG HKARVL -
Predicted molecular weight
26 kDa
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Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab43037 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
ELISA
Western blot
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Form
Liquid -
Additional notes
Immunoreactive with all sera of HIV-1 infected individuals.
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 8.5
Constituents: 48% Urea, 0.605% Tris
General Info
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Alternative names
- CA
- Capsid protein p24
- HIV-1 Gag p24
see all -
Relevance
HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. -
Cellular localization
Membrane
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab43037 has been referenced in 4 publications.
- Proulx J et al. A Non-Canonical Role for IRE1α Links ER and Mitochondria as Key Regulators of Astrocyte Dysfunction: Implications in Methamphetamine use and HIV-Associated Neurocognitive Disorders. Front Neurosci 16:906651 (2022). PubMed: 35784841
- Rosemary Bastian A et al. Mechanism of multivalent nanoparticle encounter with HIV-1 for potency enhancement of peptide triazole virus inactivation. J Biol Chem 290:529-43 (2015). PubMed: 25371202
- Gesner M et al. Fluorescence-linked Antigen Quantification (FLAQ) Assay for Fast Quantification of HIV-1 p24Gag. Bio Protoc 4:N/A (2014). PubMed: 27525295
- Hughes AJ & Herr AE Microfluidic Western blotting. Proc Natl Acad Sci U S A : (2012). SDS-PAGE . PubMed: 23223527