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Product Name
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HIV1 tat antibody [N3]
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See all HIV1 tat antibodies (9)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [N3] to HIV1 tat
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Immunogen
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Recombinant fragment: YGRKKRRQRRRA, corresponding to amino acids 47-58 of HIV1 tat
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Species Reactivity
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Reacts with HIV1 strains HxB2, BH10, IIIB and HAN,
BLAST 'YGRKKRRQRRRA' with  or 
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Epitope
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Mapped to amino acids 47-58 (YGRKKRRQRRRA – B subtype a.a. consensus, Tat basic domain)
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
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Research areas
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Microbiology >> Organism >> Virus >> RNA Virus >> ssRNA positive strand virus >> HIV
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Relevance
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HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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N3
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Isotype
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IgG3
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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Notes
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Also known as clone 02-010.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this HIV1 tat antibody [N3] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to HIV1 tat
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