You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »
 

Anti-HIV1 tat antibody [N3] (ab63957)

CodeSizePriceAbpointsAvailability
    
Add to basket
 
  • -
  •   
  •   
  •   
  •  
  •   
  •   
Updating...

Overview

Product name

Anti-HIV1 tat antibody [N3]
See all HIV1 tat products (7) ...

Description

Mouse monoclonal [N3] to HIV1 tat

Tested applications

IHC-P, ELISA, WBmore details

Cross reactivity

Reacts with HIV1 strains HxB2, BH10, IIIB and HAN,

Immunogen

Full length protein

Epitope

Mapped to amino acids 47-58 (YGRKKRRQRRRA – B subtype a.a. consensus, Tat basic domain)

General notes

Also known as clone 02-010.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: PBS, pH 7.4

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

N3

Isotype

IgG3

Research areas

Immunology >> Immune System Diseases >> Antiviral Signaling >> HIV
Microbiology >> Organism >> Virus >> RNA Virus >> ssRNA positive strand virus >> HIV

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - HIV1 tat antibody [N3] (ab63957)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - HIV1 tat antibody [N3] (ab63957) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab63957 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.

Cellular localization

Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.

Alternative names

  • p14 antibody
  • Protein Tat antibody
  • Transactivating regulatory protein antibody

Anti-HIV1 tat antibody [N3] images:

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - HIV1 tat antibody [N3] (ab63957)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - HIV1 tat antibody [N3] (ab63957)

IHC-P image of HIV1 tat staining on Transgenic mouse olfactory bulb. Heat mediated antigen retrieval was performed using trisodium citrate (pH 6). The tissue section was permeabilization using Triton x100. To block non-specififc binding, sections were blocked in 2% BSA in PBS.

Ruma Raha-Chowdhury, University Of Cambridge, United Kingdom

See Abreview

References for Anti-HIV1 tat antibody [N3] (ab63957)

ab63957 has not yet been referenced specifically in any publications.

Publishing research using ab63957? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"