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Products:Microbiology >> Organism >> Virus >> RNA Virus >> ssRNA positive strand virus >> HIV
Overview
Product name
Anti-HIV1 tat antibody
See all HIV1 tat products (7) ...
Description
Rabbit polyclonal to HIV1 tat
Specificity
This antibody is specific for Tat protein and GST-Tat fusion protein.
Tested applications
IHC-Fr, CHIPseq, WB, ELISAmore details
Cross reactivity
Reacts with HIV.
Immunogen
Recombinant full length protein expressed in E.coli.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Immunology >> Immune System Diseases >> Antiviral Signaling >> HIV
Microbiology >> Organism >> Virus >> RNA Virus >> ssRNA positive strand virus >> HIV
Applications
Show applications key
Our Abpromise guarantee covers the use of ab43014 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr: Use at an assay dependent dilution. (PubMed: 20651230)
CHIPseq: Use at an assay dependent concentration. (PubMed: 22073215)
WB: 1/20000Predicted molecular weight: 14 kDa.
ELISA
ELISA: 1/10000ELISA: 1/10000
Target
Relevance
HIV1 tat (Transactivator of Transcription) protein is a pleiotropic factor that induces a broad range of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.
Cellular localization
Nuclear. Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region.
Alternative names
- 2interacting protein antibody
- 60 kDa Tat interactive protein antibody
- cPLA antibody
see all
References for Anti-HIV1 tat antibody (ab43014)
This product has been referenced in:
- Marban Cet al. Genome-Wide Binding Map of the HIV-1 Tat Protein to the Human Genome. PLoS One 6:e26894 (2011). WB, CHIPseq; Human.Read more (PubMed: 22073215) »
- Fitting Set al. Interactive Comorbidity between Opioid Drug Abuse and HIV-1 Tat: Chronic Exposure Augments Spine Loss and Sublethal Dendritic Pathology in Striatal Neurons. Am J Pathol 177:1397-410 (2010). IHC-Fr.Read more (PubMed: 20651230) »
See all 2 publications for this product
Publishing research using ab43014? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"