Anti-HLA Class II DR4 antibody (ab98106)

Overview

• Product nameAnti-HLA Class II DR4 antibodySee all HLA Class II DR4 primary antibodies ...
• Description
  Rabbit polyclonal to HLA Class II DR4
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Monkey
• Immunogen

  Recombinant protein fragment corresponding to a region within amino acids 1 and 262 of Human HLA Class II DR4 (NP_068818).

• Positive controlRaji whole cell lysate

Properties

• FormLiquid
• Storage instructionsStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Storage bufferPreservative: 0.01% Thimerosal (merthiolate)
  Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Immunology
  • Adaptive Immunity
  • MHC
  • Class II

Applications

Target

• RelevanceHLA DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of an alpha chain (36 kDa) and a beta chain (27 kDa). It is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T helper cells. They therefore have a critical role in the initiation of the immune response.
• Cellular localizationMembrane; single pass type I membrane protein.
• Database links
  • Entrez Gene: 3123 Human
  • Entrez Gene: 3126 Human
  • Entrez Gene: 3125 Human
  • Omim: 142860 Human
  • Omim: 604776 Human
  • SwissProt: P01903 Human
  • SwissProt: Q30118 Human
  • Unigene: 520048 Human

Anti-HLA Class II DR4 antibody images

• 

  Western blot - HLA Class II DR4 antibody (ab98106)
  Anti-HLA Class II DR4 antibody (ab98106) at 1/1000 dilution + Raji whole cell lysate at 30 µg
  
  Predicted band size : 30 kDa