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Product Name
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HLA DR + DP + DQ antibody [CR3/43]
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See all HLA DR + DP + DQ antibodies (6)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [CR3/43] to HLA DR + DP + DQ
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Immunogen
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Unfortunately, this information is considered to be commercially sensitive
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Reacts with
(species key)
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Hu
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Specificity
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This antibody reacts with the beta chain of all products of the gene sub regions DP, DQ, and DR. It stains B cells, interdigitating reticulum cells, Langerhans cells and many macrophages. This antibody does not react with normal T cell and polymorphs but stains activated T cells.
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Tested applications
(see key)
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IHC-P
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: 1/25 - 1/50, in an ABC method.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Tonsil
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Cellular localization
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Membrane; Single-pass type I membrane protein.
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Research areas
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Immunology >> Adaptive Immunity >> MHC >> Class II
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Relevance
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The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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CR3/43
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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Tissue culture supernatant
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Storage buffer
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Preservative: Sodium Azide
Constituents: Tissue culture supernatant Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at +4°C.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this HLA DR + DP + DQ antibody [CR3/43] is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to HLA DR + DP + DQ
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HLA DR + DP + DQ antibody [CR3/43] - more information
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Customer reviews (feedback) regarding HLA DR + DP + DQ antibody [CR3/43] |
Customer FAQs regarding HLA DR + DP + DQ antibody [CR3/43] |
Protocols for HLA DR + DP + DQ antibody [CR3/43] |
Price and availability of products related to HLA DR + DP + DQ antibody [CR3/43] |
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HLA DR + DP + DQ antibody [CR3/43] - related products:
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HLA DR + DP + DQ antibody [CR3/43] - other tools:
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Contact Abcam with a Technical Enquiry about HLA DR + DP + DQ antibody [CR3/43] |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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