HLA DR + DP + DQ antibody [WR18] (Phycoerythrin) (ab23901)

Product Name 

HLA DR + DP + DQ antibody [WR18] (Phycoerythrin)

Product type 

Primary antibodies

Description 

Mouse monoclonal [WR18] to HLA DR + DP + DQ (Phycoerythrin)

Immunogen 

B-CLL cells (Human).

Reacts with 
(species key)

Hu

Specificity 

ab23901 recognises the common b unit of HLA-Class 2 molecules. Stains B cells, monocytes and activated T cells.

Tested applications 
(see key)

Flow Cyt

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
Flow Cyt: Use 10µl for 10⁶ cells or 100ul whole blood.

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Membrane; Single-pass type I membrane protein.

Research areas 

Immunology >> Adaptive Immunity >> MHC >> Class II

Relevance 

The major histocompatibility complex (MHC) is a large genomic region or gene family found in most vertebrates containing many genes with important immune system roles. In humans, the MHC spans almost 4 megabases of chromosome 6 and includes more than 200 known genes, of which about half have known immmunological functions. The best known genes in the MHC region are the subset that encodes cell-surface antigen-presenting proteins. In humans, these genes are referred to as human leukocyte antigen (HLA) genes. The most intensely studied HLA genes are: HLA A, HLA B, HLA C, HLA DPA, HLA DPB1, HLA DQA1, HLA DQB1, HLA DRA, and HLA DRB1. In humans, the HLA is divided into three regions: Class I, II, and III. The A, B, and C genes belong to HLA class I while the six D genes belong to class II.

Database links 

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

WR18

Myeloma 

NS1

Isotype 

IgG2a

Purity 

Protein G purified

Conjugation notes 

Purified IgG conjugated to R. Phycoerythrin (RPE)

Storage buffer 

Preservative: 0.09% Sodium Azide
Constituents: 0.1% BSA, PBS, pH 7.4

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Conjugation 

Phycoerythrin

Concentration 

0.100 mg/ml

Storage instructions 

Store at +4°C in the dark. Do not freeze.

References for HLA DR + DP + DQ antibody [WR18] (Phycoerythrin) (ab23901)

  This product has been used in:

Brignone C et al. A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells. J Immunol 179:4202-11 (2007). Flow Cyt; Human. PubMed: 17785860

If you publish research using ab23901 please let us know so that we can cite the reference on this datasheet.

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