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Anti-HPD antibody [EPR5296] (ab108506)

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Overview

Product name

Anti-HPD antibody [EPR5296]
See all HPD products (5) ...

Description

Rabbit monoclonal [EPR5296] to HPD

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Does not react with

Mouse, Rat

Immunogen

A synthetic peptide corresponding to residues in Human HPD

Positive control

HepG2 and fetal liver lysates.

General notes

Produced under U.S. Patent No. 5,675,063

Properties

Form

Liquid

Storage instructions

Store at -20°C. Stable for 12 months at -20°C

Storage buffer

PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

EPR5296

Isotype

IgG1

Research areas

Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Redox metabolism >> Oxidative stress
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Amino acid metabolism
Cell Biology >> Other Antibodies >> Oxidative Stress
Signal Transduction >> Metabolism >> Amino Acids

  • Western blot - HPD antibody [EPR5296] (ab108506)Western blot - HPD antibody [EPR5296] (ab108506) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab108506 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/1000 - 1/10000. De...Read more →

    WB: 1/1000 - 1/10000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

Application notes

Is unsuitable for ,Flow Cyt,ICC,IHC-P or IP.

Target

Relevance

HPD participates in the tyrosine catabolic pathway by catalyzing the conversion of 4-hydroxyphenylpyruvate to homogentisate. The mechanism of action of HPD involves a decarboxylation step and an oxidation step, followed by a rearrangement step to form homogentisic acid. Alterations in the structure and activity of HPD are causally related to two different metabolic disorders, the recessively inherited tyrosinemia type III and the dominantly inherited hawkinsinuria.

Cellular localization

Cytoplasmic

Alternative names

  • 4 HPPD antibody
  • 4 hydroxyphenylpyruvate dioxygenase antibody
  • 4 hydroxyphenylpyruvic acid oxidase antibody
  • 4HPPD antibody
  • GLOD3 antibody
  • glyoxalase domain containing 3 antibody
  • HPPDase antibody
  • PPD antibody
see all

Database links

Anti-HPD antibody [EPR5296] images:

  Western blot - HPD antibody [EPR5296] (ab108506)

Western blot - HPD antibody [EPR5296] (ab108506)

All lanes : Anti-HPD antibody [EPR5296] (ab108506) at 1/1000 dilution

Lane 1 : HepG2 lysate.
Lane 2 : Fetal liver lysate.

Lysates/proteins at 10 µg per lane.


Predicted band size : 45 kDa
Observed band size : 45 kDa

References for Anti-HPD antibody [EPR5296] (ab108506)

ab108506 has not yet been referenced specifically in any publications.

Publishing research using ab108506? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"